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Myosin Related Products (90)
Related Products (90)
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MT-134
0 ImagesCat. No.: HY-141810CAS No.: 2968308-52-1MT-134 is a SkMII-specific inhibitor and has excellent exposure in muscles.
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CK-571
0 ImagesCat. No.: HY-180792CAS No.: 1119536-89-8CK-571 is a potent and selective inhibitor of smooth muscle myosin-2 (SMM), with an IC50 value of 86 nM. CK-571 exhibits IC50 values for cardiac muscle myosin (CMM), skeletal muscle myosin (SKM), and non-muscle myosin-2A (NMM-2A) of 2.3, 42, and 0.58 μM, respectively. CK-571 can be used for research on asthma, chronic obstructive pulmonary disease, and other smooth muscle-related diseases.
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Myosin I-IN-1
0 ImagesCat. No.: HY-189346Myosin I-IN-1 is an Antifungal agent and Myosin I inhibitor with a Kd of 0.14 μM for FgMyoI. Myosin I-IN-1 inhibits mycelial growth, sporulation, spore germination, and Deoxynivalenol (HY-N6684) biosynthesis. Myosin I-IN-1 disrupts cell wall and cell membrane integrity and induces hyphal morphological changes. Myosin I-IN-1 exhibits broad-spectrum antifungal activity against plant pathogenic fungi. Myosin I-IN-1 shows protective efficacy against Fusarium head blight in wheat and maize. Myosin I-IN-1 can be used for research on Fusarium head blight.
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Myosin-IN-4
0 ImagesCat. No.: HY-17680CAS No.: 2823425-92-7Myosin-IN-4 (Compound 3), a pyridine-2,4-dione derivative, is a myocardial myosin inhibitor. Myosin-IN-4 has a strong inhibitory activity against cardiac myosin ATPase with an IC50 value of 0.73 μM. Myosin-IN-4 exert a negative inotropic effect by inhibiting myocardial contraction. Myosin-IN-4 can be used for the research on cardiovascular diseases related to cardiac myosin.
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(-)-Blebbistatin (GMP)
0 ImagesCat. No.: HY-13441GCAS No.: 856925-71-8(-)-Blebbistatin (GMP) is (-)-Blebbistatin (HY-13441) produced by using GMP guidelines. (-)-Blebbistatin (GMP) is a selective inhibitor of the ATPase activity of non-muscle myosin II.
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Myosin modulator 1
0 ImagesCat. No.: HY-161608CAS No.: 3034189-56-2
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Myokinasib-II
0 ImagesCat. No.: HY-169183Myokinasib-II is a MLCK1 inhibitor with an IC50 of 4.4 μM. Myokinasib-II induces cell cortex softening, impairs cell migration capacity, induces multinucleation, reduces cell stiffness, alters membrane tether dynamics, decreases actomyosin tension and changes nuclear morphology. Myokinasib-II is a MLCK1 chemical biology probe with a unique structure that does not depolymerize tubulin and maintains cell viability even under high-concentration treatment in fibroblasts.
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Myosin modulator 2
0 ImagesCat. No.: HY-161609CAS No.: 3034189-87-9
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Adhibin
0 ImagesCat. No.: HY-170318Adhibin is an allosteric inhibitor for RhoGAP class IX myosin, that inhibits Myo9 ATPase in mammalian and invertebrate with IC50 of 2.5 µM and 2.6 µM. Adhibin binds to the ATPase of myosin, interfers with its motor function, blocks the RhoGTPase related signaling pathway, and affects the cell migration, adhesion and cell division. Adhibin can be used in research about cancer metastasis.
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Danicamtiv-d3
0 ImagesCat. No.: HY-109128S1CAS No.: 2925925-82-0Synonyms: MYK-491-d3Danicamtiv-d3 (MYK-491-d3) is a deuterated labeled Danicamtiv (HY-109128). Danicamtiv (MYK-491), an inotropic agent, is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency.
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Blebbistatin (Standard)
0 ImagesBlebbistatin (Standard) is the analytical standard of Blebbistatin. This product is intended for research and analytical applications. Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor, promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing, and better preserves cell junctional integrity and barrier function. Blebbistatin blocks cell migration.
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ZJS178
0 ImagesCat. No.: HY-179120CAS No.: 3095661-21-2ZJS178 is a novel inhibitor of myosin I. ZJS178 is a fungicide that has inhibitory activity against Fusarium graminearum and can reduce DON toxin synthesis. ZJS178 can be used for research on plant diseases such as wheat scab.
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ML-7
0 ImagesCat. No.: HY-119038CAS No.: 109376-83-2ML-7 is a selective and highly specific myosin light chain kinase (MLCK) inhibitor that acts as a trabecular meshwork (TM) relaxant. ML-7 enhances Quinocetone (HY-123581)-induced phosphorylation of ERK, p38 MAPK and JNK, attenuates Akt activation, and promotes apoptosis of hepatocellular carcinoma cells. ML-7 reduces Th2 cytokine secretion by inhibiting MLCK, while alleviating smooth muscle hyperplasia and collagen deposition. As a non-antibiotic adjuvant, ML-7 restores the sensitivity of drug-resistant bacteria to Tigecycline (HY-B0117). ML-7 can be used in research related to glaucoma, hepatocellular carcinoma, asthma, and Klebsiella pneumoniae infection.
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Mavacamten-d6
0 ImagesCat. No.: HY-109037SCAS No.: 2453251-18-6Synonyms: MYK461-d6; SAR439152-d6Mavacamten-d6 (MYK461-d6; SAR439152-d6) is deuterium labeled Mavacamten (HY-109037). Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively.
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R-(-)-7-Desmethyl-8-nitro blebbistatin
0 ImagesCat. No.: HY-133885ACAS No.: 1217619-62-9R-(-)-7-Desmethyl-8-nitro blebbistatin is an analog of (-)-Blebbistatin (HY-13441). (-)-Blebbistatin is a selective non-muscle myosin II inhibitor.
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Tubercidin 5'-triphosphate tetrasodium
0 ImagesCat. No.: HY-134248ASynonyms: 7-Deazaadenosine 5'-triphosphate tetrasodium
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W-7 hydrochloride (Standard)
0 ImagesCat. No.: HY-100912RCAS No.: 61714-27-0W-7 (hydrochloride) (Standard) is the analytical standard of W-7 (hydrochloride) (HY-100912). This product is intended for research and analytical applications. W-7 hydrochloride is a selective calmodulin antagonist. W-7 hydrochloride inhibits the Ca2+-calmodulin-dependent phosphodiesterase and myosin light chain kinase with IC50 values of 28 μM and 51 μM, respectively. W-7 hydrochloride induces apoptosis and has antitumor and vascular relaxing activity. W-7 hydrochloride is a blocker of Kv4.3 and can be used for research of arrhythmias.
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(+)-Blebbistatin (Standard)
0 ImagesCat. No.: HY-107657RCAS No.: 1177356-70-5(+)-Blebbistatin (Standard) is the analytical standard of (+)-Blebbistatin (HY-107657). This product is intended for research and analytical applications. (+)-Blebbistatin is the inactive enantiomer of (-)-Blebbistatin (HY-13441). (-)-Blebbistatin is a selective inhibitor of non-muscle myosin II ATPase activity.
