2. Signaling Pathways
  3. NF-κB
  4. NF-κB
  5. NF-κB Ligand

NF-κB Ligand

NF-κB Isoform Comparison

NF-κB Ligands (2):

Cat. No. Product Name Effect Purity
  • HY-N2397
    9''-Methyl salvianolate B
    		Ligand 99.54%
    9''-Methyl salvianolate B (MSB) is a blood-brain barrier-permeable inhibitor with high affinity for g5Rp, with a Kd value of 117 nM against African swine fever virus (ASFV) g5Rp. 9''-Methyl salvianolate B also acts as a ZBP1 inhibitor. It exhibits strong binding affinity to key proteins in the PPARγ/NF-κB pathway. 9''-Methyl salvianolate B blocks the interaction between ASFV g5Rp and host proteins eIF5A or RPS15. It restores hypusination modification of eIF5A, promotes autophagy (Autophagy), and inhibits ASFV replication. 9''-Methyl salvianolate B effectively disrupts ZBP1-mediated PANoptosome assembly. It effectively alleviates myocardial ischemia/reperfusion injury. 9''-Methyl salvianolate B can be used in studies related to African swine fever.
  • HY-176061
    NIK ligand 1
    		Ligand
    NIK ligand 1 (compound 2) is a NF-κB inducing kinase (NIK) ligand.