Survivin Degrader
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PROTAC survivin degrader-1
0 ImagesCat. No.: HY-186212CAS No.: 3079079-69-6
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UC-112
0 ImagesUC-112 is a XIAP inhibitor with anticancer activity. UC-112 selectively downregulates and degrades survivin via the ubiquitin-mediated proteasomal degradation pathway. UC-112 reduces XIAP levels in in vivo tumor models. UC-112 activates caspase-3/7 and caspase-9, and induces cancer cell apoptosis. UC-112 is applicable to studies on melanoma, prostate cancer and cancer-related research.
