2. Signaling Pathways
  3. Apoptosis
    Autophagy
    Cell Cycle/DNA Damage
    Immunology/Inflammation
  4. FKBP
  5. FKBP12 Isoform
  6. FKBP12 Modulator

FKBP12 Modulator

FKBP12 Modulators (2):

Cat. No. Product Name Effect Purity
  • HY-112210
    Shield-1
    		Modulator 99.73%
    Shield-1 (Shld1) is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize proteins tagged with a mutated FKBP12-derived destabilization domain (DD).
  • HY-153806
    RapaBlock
    		Modulator 98.0%
    RapaBlock is a potent, non-immunosuppressive and brain-impermeable FKBP12 ligand.