2. Signaling Pathways
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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D0108
    Fluorescein dilaurate
    Fluorescein dilaurate is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
    Fluorescein dilaurate
  • HY-D0029
    5(6)-Aminofluorescein
    		98.55%
    5(6)-Aminofluorescein (5(6)-AFM) is an amino-containing fluorescein dye primarily used for biomolecular labeling, fluorescence imaging, and as a precursor for the synthesis of fluorescent probes (Ex/Em = 495/515 nm).
    5(6)-Aminofluorescein
  • HY-W248587
    Cryptocyanine
    		99.15%
    Cryptocyanine is a fluorescent dye.
    Cryptocyanine
  • HY-D1374
    Sulfo-Cy5 carboxylic acid potassium
    Sulfo-Cy5 carboxylic acid potassium is a water-soluble, inactive Cy5 carboxylic acid.
    Sulfo-Cy5 carboxylic acid potassium
  • HY-D3446
    PA-SiR-Halo
    PA-SiR-Halo is a photoactivatable fluorophore targeting HaloTag. When bound to HaloTag, PA-SiR-Halo stabilizes its fluorescent form under physiological pH. After conjugation and photoactivation, it exhibits enhanced resistance to nucleophiles, and enables live-cell confocal imaging, fixed-cell single-molecule localization microscopy imaging, live-cell single-particle tracking, as well as live-cell single-molecule localization microscopy imaging of dynamic mitochondrial structures without the need for washing.
    PA-SiR-Halo
  • HY-172166A
    TRITC-lysine-dextran (MW 10kDa)
    TRITC-lysine-dextran, 10kDa is a dextran with lysine coupling with a fluorescent group TRITC (HY-D0791). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone.
    TRITC-lysine-dextran (MW 10kDa)
  • HY-168322
    2-Hydroxy nile red trifluoromethanesulfonate
    		98.36%
    2-Hydroxy nile red trifluoromethanesulfonate is a fluorescent probe, that enters into oligodeoxyribonucleic acid as a nucleotide replacement. 2-Hydroxy nile red trifluoromethanesulfonate can be used as a DNA probe for detecting the polar changes in tumor microenvironments.
    2-Hydroxy nile red trifluoromethanesulfonate
  • HY-66020
    6-FITC
    6-FITC (6-Fluorescein Isothiocyanate) is a fluorescein isomer and also serves as a fluorescent label for biomolecules (FITC isomers have similar excitation/emission wavelengths, which are 495 nm/519 nm in fluorescence detection).
    6-FITC
  • HY-16710
    GPDA
    		99.99%
    GPDA (GPN; Glycylproline p-nitroanilide tosylate) is a chromogenic substrate of prolyl dipeptidyl aminopeptidase. GPDA is used to detect the activity of prolyl dipeptidyl aminopeptidase in human serum.
    GPDA
  • HY-D0711R
    Indocyanine green (Standard)
    Indocyanine green (Standard) is the analytical standard of Indocyanine green. This product is intended for research and analytical applications. Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography.
    Indocyanine green (Standard)
  • HY-129594
    DANP
    DANP is a bulge base recognition probe that strongly and specifically binds to the single cytosine and thymine bulges. DANP could stabilize not only a single cytosine but also the thymine bulge in duplex DNA.
    DANP
  • HY-D2647
    Cy5 HA (MW 500000)
    Cy5 HA (MW 500000) is a hyaluronic acid labeled with CY5 (HY-D0821). Cy5 HA (MW 500000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 633/670 nm).
    Cy5 HA (MW 500000)
  • HY-D0233
    Leucocrystal violet
    		98.81%
    Leucocrystal violet is a cationic triarylmethane dye. Leucocrystal violet generates a colored purple product in the presence of hydrogen peroxide and horseradish peroxidase, or when oxidized by periodate under the catalysis of horseradish peroxidase. Leucocrystal violet serves as a chromogenic reagent for the determination of submicrogram-level hydrogen peroxide, with no interference from tryptophan, persulfate or chromate. Leucocrystal violet reacts with blood to produce a purple/violet color in the presence of hydrogen peroxide; it forms a very weak fluorophore when acting with whole blood in an unbuffered solution, with a maximum absorption wavelength of 630 nm and a maximum fluorescence emission wavelength of 665 nm upon excitation at 630 nm. Leucocrystal violet is widely used for staining blood residues on porous and non-porous materials.
    Leucocrystal violet
  • HY-172164A
    FITC-lysine-dextran (MW 10kDa)
    FITC-lysine-dextran, 10kDa is a dextran with lysine coupling with a fluorescent group FITC (HY-66019). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone.
    FITC-lysine-dextran (MW 10kDa)
  • HY-130783
    LysoFP-NO2
    		98.2%
    LysoFP-NO2 is a turn-on fluorescent probe for carbon monoxide (CO) that localizes to the lysosome. In the presence of lysosomal CO, lysoFP-NO2 is transformed into lysoFP-NH2, which is highly fluorescent. LysoFP-NO2 is selective for CO over various reactive nitrogen, oxygen, and sulfur species. It displays excitation/emission maxima of 440/528 nm, respectively, and is not cytotoxic to HepG2 cells for up to five hours when used at a concentration of 30 μM.
    LysoFP-NO2
  • HY-141575
    C12-NBD-ceramide
    		98.97%
    C12-NBD-ceramide is a fluorescent analogue of ceramide, it can be used as a substrate in ceramidase assays.
    C12-NBD-ceramide
  • HY-W998707
    TAMRA amine, 5-isomer hydrochloride
    TAMRA amine, 5-isomer hydrochloride is a rhodamine dye with excitation/emission maximum 553/575 nm. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
    TAMRA amine, 5-isomer hydrochloride
  • HY-15632
    para-iodoHoechst 33258
    		98.94%
    para-iodoHoechst 33258 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution.
    para-iodoHoechst 33258
  • HY-113238F
    FITC-Lithocholic acid 3-sulfate
    FITC-Lithocholic acid 3-sulfate (FITC-Sulfolithocholic acid) is a FITC-labeled Lithocholic acid 3-sulfate, which is a sulfated biliary metabolite. Lithocholic acid 3-sulfate selectively inhibits Th17 cell differentiation by targeting RORγt. Lithocholic acid 3-sulfate can be used for the research of pathogenesis of cholestatic liver diseases.
    FITC-Lithocholic acid 3-sulfate
  • HY-D1569
    CellTracker Orange CMRA Dye (5/6-mixture)
    		98.0%
    CellTracker Orange CMRA Dye is a fluorescent dye. CellTracker Orange CMRA Dye can be used for cell imaging and monitoring the movement and location of cells.
    CellTracker Orange CMRA Dye (5/6-mixture)
Cat. No. Product Name / Synonyms Application Reactivity