2. Signaling Pathways
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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-156304
    Coumarin-C2-TCO
    		98.10%
    Coumarin-C2-TCO is a dye derivative of Coumarin (HY-N0709). Coumarin-C2-TCO utilizes its TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
    Coumarin-C2-TCO
  • HY-D2840I
    FITC-mPEG20000
    FITC-mPEG20000 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG20000 can be used for fluorescent labeling and imaging.
    FITC-mPEG20000
  • HY-D1221
    6-Fluorescein phosphoramidite
    		98.0%
    6-Fluorescein phosphoramidite is a potent fluorescent dye. 6-Fluorescein phosphoramidite can be used to label oligonucleotides.
    6-Fluorescein phosphoramidite
  • HY-D2836A
    FITC-HA (MW 500000)
    FITC-HA (MW 500000) is hyaluronic acid (HA) (HY-B0633A) labeled with FITC (HY-66019). FITC-HA retains the ability of HA to bind to receptors (such as CD44) and form extracellular matrices, while it can be detected by fluorescence microscopy or flow cytometry for tracing the localization, binding, internalization and metabolic pathways of HA in cells, tissues or living organisms (Ex/Em ≈ 490/520 nM).
    FITC-HA (MW 500000)
  • HY-136404
    Melanin probe-1
    		98.06%
    Melanin probe-1 is an 18F-picolinamides based PET probe. Melanin probe-1 can be used for PET imaging of malignant melanoma. Melanin probe-1 exhibits high tumor targeting efficiency, excellent tumor imaging contrasts, desirable biodistribution patterns, and good in vivo stability.
    Melanin probe-1
  • HY-116070
    Iodoantipyrine
    		≥98.0%
    Iodoantipyrine (4-Iodoantipyrine) is an iodinated Antipyrine (HY-B0171) with potential antiviral activity. Antipyrine (Phenazone) is an antipyretic and analgesic that also serves as a molecular probe of hepatic oxidative metabolites.
    Iodoantipyrine
  • HY-155327
    Cy3-PEG2-endo-BCN
    Cy3-PEG2-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
    Cy3-PEG2-endo-BCN
  • HY-D0305
    Tropaeolin O
    Tropaeolin O is an acidic monoazo dye that undergoes a coupling reaction under pH=10.5 conditions to form a blue disazo dye. Tropaeolin O can be used for the determination of palladium(II), osmium(IV), albumin, and casein.
    Tropaeolin O
  • HY-D0097
    7-Fluorobenzofurazan-4-sulfonic acid ammonium
    		98.96%
    7-Fluorobenzofurazan-4-sulfonic acid ammonium is a fluorescent label. 7-Fluorobenzofurazan-4-sulfonic acid ammonium can be used for detecting dissolved thiol-disulfide (e.g., Cys, GSH).
    7-Fluorobenzofurazan-4-sulfonic acid ammonium
  • HY-D1881A
    Sulfo-Cy7 carboxylic acid TEA
    		98.23%
    Sulfo-Cy7 carboxylic acid TEA (compound 6m) is a cyanine dye.
    Sulfo-Cy7 carboxylic acid TEA
  • HY-153349
    2,3-Di(furan-2-yl)quinoxaline
    		98.30%
    2,3-Di(furan-2-yl)quinoxaline (Compound 5) is a quinoxaline exhibiting blue fluorescence. 2,3-Di(furan-2-yl)quinoxaline is cell permeable and sufficiently bright at a micromolar concentration (1.5 μM).
    2,3-Di(furan-2-yl)quinoxaline
  • HY-D3381
    MitoCLox
    		99.59%
    MitoCLox is a mitochondria-targeted ratiometric fluorescent probe for measuring mitochondrial inner membrane lipid peroxidation.
    MitoCLox
  • HY-D2551
    Cy5-PEG5000-FA
    Cy5-PEG5000-FA is a fluorescently labeled biomolecule consisting of Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG), and Folic acid (FA) (HY-16637). Cy5 is commonly used in applications such as immunolabeling and nucleic acid labeling. The maximum emission wavelength of Cy5 is approximately 670 nm.
    Cy5-PEG5000-FA
  • HY-179074H
    FITC-Polysucrose 400
    FITC-Polysucrose 400 is FITC-labeled Polysucrose 400 (HY-131960). FITC-Polysucrose 400 is mainly used for permeability and microcirculation studies (Ex/Em = 488/525 nm).
    FITC-Polysucrose 400
  • HY-136884
    DAR-4M
    		98.9%
    DAR-4M is a fluorescent indicator for nitric oxide (NO) based on the rhodamine chromophore (Ex/Em= 550/572 nm).
    DAR-4M
  • HY-W141825
    N-Acetyl-DL-phenylalanine β-naphthyl ester
    N-Acetyl-DL-phenylalanine β-naphthyl ester is an aromatic amino acid ester, which functions as a chromogenic substrate for chymotrypsin and microbial serine proteases such as subtilisin.
    N-Acetyl-DL-phenylalanine β-naphthyl ester
  • HY-D1942
    ATTO 590 biotin
    ATTO 590 Biotin is a biotin derivative of ATTO 590 with maximum excitation/emission wavelengths: 594/622 nm.
    ATTO 590 biotin
  • HY-D1512
    Oxonol 595
    		99.98%
    Oxonol 595 is a voltage-sensitive fluorescent dye.
    Oxonol 595
  • HY-D2893M
    RB-PEG20000-RB
    RB-PEG20000-RB (Rhodamine B-PEG20000-Rhodamine B) a fluorescent dye composed of two Rhodamine B (HY-Y0016) and PEG. RB-PEG20000-RB can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm).
    RB-PEG20000-RB
  • HY-D1799
    Vari Fluor 568 SE
    Vari Fluor 568 SE (VF 568 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=573 nm/595 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.
    Vari Fluor 568 SE
Cat. No. Product Name / Synonyms Application Reactivity