2. Signaling Pathways
  3. Immunology/Inflammation
  4. Mucin
  5. Mucin Chemical

Mucin Chemical

Mucin Isoform Comparison

Mucin Chemicals (4):

Cat. No. Product Name Effect Purity
  • HY-160062
    S2.2 aptamer sodium
    		Chemical
    S2.2 aptamer sodium is a nucleic acid-based MUC1-binding aptamer with high affinity and low toxicity. Upon binding to its target, S2.2 aptamer sodium undergoes a conformational switch and restores fluorescence signal, serving as a targeted imaging agent for MUC1-positive cancer cells. S2.2 aptamer sodium enables targeted delivery to breast cancer cells with overexpressed MUC1. When formulated as the S2.2-PEG-MZF molecular probe, S2.2 aptamer sodium possesses the functions of T2 signal inhibition, magnetic field-induced hyperthermia and targeted magnetic resonance molecular imaging. In the S2.2-PEG-MZF/DOX nanoliposome, S2.2 aptamer sodium supports targeted thermochemotherapy, effectively inhibiting cancer cell proliferation and invasion as well as inducing apoptosis, and is widely used in studies related to breast cancer.
  • HY-160060
    MA3 aptamer sodium
    		Chemical
    MA3 aptamer sodium is an 86-base long DNA aptamer targeting the mucin MUC1. MA3 aptamer sodium binds to the peptide epitope of mucin 1 (MUC1) with a Kd of 38.3 nM and has minimal cross-reactivity with albumin.
  • HY-160062A
    S2.2 aptamer sodium scrambled negative control
    		Chemical
    S2.2 aptamer sodium scrambled negative control is the sequence scrambled negative control of S2.2 aptamer sodium.
  • HY-160060A
    MA3 aptamer sodium scrambled negative control
    		Chemical
    MA3 aptamer sodium scrambled negative control is the sequence scrambled negative control of MA3 aptamer sodium.