- Signaling Pathways
- Others
- Reference Standards
Reference Standards
-
Reference Standards Related Products (11771)
Related Products (11771)
-
Capmatinib dihydrochloride hydrate (Standard)
0 ImagesSynonyms: INC280 dihydrochloride hydrate (Standard); INCB-28060 dihydrochloride hydrate (Standard)Capmatinib (dihydrochloride hydrate) (Standard) is the analytical standard of Capmatinib (dihydrochloride hydrate). This product is intended for research and analytical applications. Capmatinib (INC280; INCB28060) dihydrochloride hydrate is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor (IC50=0.13 nM). Capmatinib dihydrochloride hydrate can inhibit phosphorylation of c-MET as well as c-MET pathway downstream effectors such as ERK1/2, AKT, FAK, GAB1, and STAT3/5. Capmatinib dihydrochloride hydrate potently inhibits c-MET-dependent tumor cell proliferation and migration and effectively induces apoptosis. Antitumor activity. Capmatinib dihydrochloride hydrate is largely metabolized by CYP3A4 and aldehyde oxidase. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
LDN-211904 oxalate (Standard)
0 ImagesCat. No.: HY-107460RCAS No.: 1198408-78-4LDN-211904 oxalate (Standard) is the analytical standard of LDN-211904 (oxalate) (HY-107460). This product is intended for research and analytical applications. LDN-211904 oxalate is a potent and reversible EphB3 inhibitor with an IC50 of 79 nM. LDN-211904 oxalate shows good metabolic stability in mouse liver microsomes. LDN-211904 oxalate with Cetuximab (HY-P9905) could be effective in inhibiting STAT3-activated colorectal cancer (CRC) stemness and Cetuximab resistance in CRC. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
Methyl palmitoleate (Standard)
0 ImagesSynonyms: (Z)-Methyl hexadec-9-enoate (Standard); Methyl cis-9-Hexadecenoate (Standard)Methyl palmitoleate (Standard) is the analytical standard of Methyl palmitoleate. This product is intended for research and analytical applications. Methyl palmitoleate ((Z)-Methyl hexadec-9-enoate), a fatty acid methyl ester, is an analogue of Palmitoleate with cytoprotective and growth-promoting properties. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
Azido-PEG2-CH2COOH CHA (Standard)
0 ImagesCat. No.: HY-108368ARCAS No.: 2098500-94-6Azido-PEG2-CH2COOH CHA (Standard) is the analytical standard of Azido-PEG2-CH2COOH (CHA) (HY-108368A). This product is intended for research and analytical applications. Azido-PEG2-CH2COOH (CHA) is a azido-modified PEG2 acid, can be used as a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
Decloxizine (Standard)
0 ImagesDecloxizine (UCB-1402; NSC289116) (Standard) is the analytical standard of Decloxizine. This product is intended for research and analytical applications.Decloxizine is an orally active bronchodilator that can penetrate the blood-brain barrier. Decloxizine is a piperazine-type H1 histamine receptor antagonist. Decloxizine selectively blocks H1 histamine receptors, inhibiting histamine-induced capillary dilation, edema, and itching. Decloxizine has some 5-HT2 receptor antagonistic activity. Decloxizine can be used in studies of urticaria, allergic rhinitis, and bronchial asthma. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
Patent Blue V calcium salt (Standard)
0 ImagesPatent Blue V (calcium salt) (Standard) is the analytical standard of Patent Blue V (calcium salt). This product is intended for research and analytical applications. Patent Blue V has been widely used in sentinel lymph node mapping. Patent Blue V is also a food coloring agent and an alternative dye for trypan blue (TB) in descemet membrane endothelial keratoplasty (DMEK). -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
RO4929097 (Standard)
0 ImagesCat. No.: HY-11102RCAS No.: 847925-91-1Synonyms: RG-4733 (Standard)RO4929097 (Standard) is the analytical standard of RO4929097 (HY-11102). This product is intended for research and analytical applications. RO4929097 (RG-4733) is an orally active γ secretase inhibitor with an IC50 of 4 nM, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
Dimethomorph (Standard)
0 ImagesDimethomorph (Standard) is the analytical standard of Dimethomorph. This product is intended for research and analytical applications. Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 µM. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1H-tetrazole (Standard)
0 ImagesCat. No.: HY-124255RCAS No.: 120568-11-8Synonyms: Losartan impurity 4 (Standard)Losartan impurity E (Standard) is the analytical standard of Losartan impurity E. This product is intended for research and analytical applications. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
CK-666 (Standard)
0 ImagesCat. No.: HY-16926RCAS No.: 442633-00-3CK-666 (Standard) is the analytical standard of CK-666 (HY-16926). This product is intended for research and analytical applications. CK-666 is a cell-permeable actin-related protein Arp2/3 complex inhibitor (IC50=12 μM). CK-666 binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocKing movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
trans-3,5-Dimethoxystilbene (Standard)
0 ImagesCat. No.: HY-W278867RCAS No.: 21956-56-9Synonyms: trans-Pinosylvin dimethyl ether (Standard)trans-3,5-Dimethoxystilbene (Standard) is the analytical standard of trans-3,5-Dimethoxystilbene (HY-W278867). This product is intended for research and analytical applications. trans-3,5-Dimethoxystilbene (trans-Pinosylvin dimethyl ether) is a natural stilbenoid metabolite. trans-3,5-Dimethoxystilbene acts as an acetylcholinesterase inhibitor with a IC50 of 9 μM against Electrophorus electricus acetylcholinesterase. trans-3,5-Dimethoxystilbene binds to acetylcholinesterase and blocks acetylcholine hydrolysis, thereby increasing acetylcholine levels in the cholinergic synaptic cleft. trans-,5-Dimethoxystilbene can be used in the research of neurodegenerative diseases such as Alzheimer's disease. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
Perfluamine (Standard)
0 ImagesCat. No.: HY-108299RCAS No.: 338-83-0Synonyms: Perfluorotripropylamine (Standard); FTPA (Standard); Tris(perfluoropropyl)amine (Standard)Perfluamine (Standard) is the analytical standard of Perfluamine (HY-108299). This product is intended for research and analytical applications. Perfluamine (Perfluorotripropylamine), a hydrophobic carrier fluid, is used in the surface modification of droplet polymeric microfluidic devices. Perfluamine has a role as a blood substitute. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
Raltegravir potassium (Standard)
0 ImagesCat. No.: HY-10353ARCAS No.: 871038-72-1Synonyms: MK 0518 potassium (Standard)Raltegravir (potassium) (Standard) is the analytical standard of Raltegravir (potassium). This product is intended for research and analytical applications. Raltegravir (MK 0518) potassium is a potent integrase (IN) inhibitor, used to treat HIV infection. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
Brensocatib (Standard)
0 ImagesCat. No.: HY-101056RCAS No.: 1802148-05-5Synonyms: AZD7986 (Standard); INS 1007 (Standard)Brensocatib (Standard) is the analytical standard of Brensocatib (HY-101056). This product is intended for research and analytical applications. Brensocatib (AZD7986) is an oral dipeptidyl peptidase 1 (DPP1) inhibitor with pIC50s of 6.85, 7.6, 7.7, 7.8, and 7.8 in human, mouse, rat, dog and rabbit, respectively. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
Methocarbamol (Standard)
0 ImagesMethocarbamol (Standard) is the analytical standard of Methocarbamol. This product is intended for research and analytical applications. Methocarbamol is an orally active central muscle relaxant and blocks muscular Nav1.4 channel. Methocarbamol reversibly affects voltage dependence of inactivation of Nav1.4 channel. Methocarbamol has the potential for muscle spasms and pain syndromes research. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
HC-067047 (Standard)
0 ImagesHC-067047 (Standard) is the analytical standard of HC-067047 (HY-100208). This product is intended for research and analytical applications. HC-067047 is a potent and selective TRPV4 antagonist and reversibly inhibits currents through the human, rat, and mouse TRPV4 orthologs with IC50 values of 48 nM, 133 nM, and 17 nM, respectively. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
Manidipine (Standard)
0 ImagesManidipine (Standard) is the analytical standard of Manidipine. This product is intended for research and analytical applications. Manidipine is an orally active calcium channel antagonist. Manidipine regulates the expression of cytokines (IL-1β, IL-6). Manidipine has a hypotensive effect. Manidipine can be used in the study of cardiovascular diseases (such as hypertension, myocardial ischemia-reperfusion injury, ventricular hypertrophy), kidney diseases (such as glomerular diseases), and epilepsy. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
ML115 (Standard)
0 ImagesCat. No.: HY-111152RCAS No.: 912798-42-6ML115 (Standard) is the analytical standard of ML115 (HY-111152). This product is intended for research and analytical applications. ML115, a molecular probe of the signal transducer, is a selective STAT3 agonist, with an EC50 of 2 nM. ML115 increases the expression of BCL3, a known STAT3-dependent oncogene. ML115 is inactive against the related STAT1, STAT5 and NF-κB anti-targets. ML115 counteracts the effects of Ginsenoside Rc (HY-N0042) on cell viability and inflammatory responses in LPS (HY-D1056)-stimulated H9c2 and RAW264.7 cells, while altering oxidative stress markers. ML115 can be used for the study of breast and prostate cancers. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
Cephaeline dihydrochloride (Standard)
0 ImagesSynonyms: (-)-Cephaeline dihydrochloride (Standard); NSC 32944 (Standard)Cephaeline (dihydrochloride) (Standard) is the analytical standard of Cephaeline (dihydrochloride). This product is intended for research and analytical applications. Cephaeline dihydrochloride is a selective CYP2D6 inhibtor with an IC50 of 121 μM. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -
-
Artemisone (Standard)
0 ImagesCat. No.: HY-19502RCAS No.: 255730-18-8Synonyms: Artemifone (Standard); BAY 44-9585 (Standard)Artemisone (Standard) is the analytical standard of Artemisone. This product is intended for research and analytical applications. Artemisone (Artemifone) is a potent and semi-synthetic antimalarial, inhibits P. falciparum strains, with a mean IC50 of 0.83 nM. Artemisone is also a potent inhibitor of human CMV. -
loading...Please select quantityGet Quote
August 31
-
Please select quantity
August 31
Get Quote
loading... -