847925-91-1
847925-91-1
Chemical Structure
RO4929097
- CAS No.: 847925-91-1
- Formula:C22H20F5N3O3
- Molecular Weight:469.40
IUPAC Name: (S)-2,2-dimethyl-N1-(6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-N3-(2,2,3,3,3-pentafluoropropyl)malonamide
InChIKey: OJPLJFIFUQPSJR-INIZCTEOSA-N
SMILES: O=C(C(C)(C(NCC(F)(C(F)(F)F)F)=O)C)N[C@H]1C2=CC=CC=C2C3=CC=CC=C3NC1=O
Biological Activity: RO4929097 is an orally active γ secretase inhibitor with an IC50 of 4 nM, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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RO4929097 | 98.64% | RO4929097 is an orally active γ secretase inhibitor with an IC50 of 4 nM, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively. | ||||||||||||||||||||
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References
Keywords
