1. Metabolic Enzyme/Protease
  2. ROR

AZD-0284 

Cat. No.: HY-120384
Handling Instructions

AZD-0284 is an inverse agonist of the nuclear receptor RORγ. In development for the treatment of plaque psoriasis vulgaris and respiratory tract disorders.

For research use only. We do not sell to patients.

AZD-0284 Chemical Structure

AZD-0284 Chemical Structure

CAS No. : 2101291-07-8

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

AZD-0284 is an inverse agonist of the nuclear receptor RORγ. In development for the treatment of plaque psoriasis vulgaris and respiratory tract disorders[1].

IC50 & Target

RORγ[1]

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9068 mL 9.5342 mL 19.0683 mL
5 mM 0.3814 mL 1.9068 mL 3.8137 mL
10 mM 0.1907 mL 0.9534 mL 1.9068 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

524.43

Formula

C₂₁H₁₈F₆N₂O₅S

CAS No.

2101291-07-8

SMILES

O=C([[email protected]@H]1N(C(C)=O)CC2=C1C=CC(S(=O)(C)=O)=C2)NC3=CC=C(C(C(F)(F)F)(O)C(F)(F)F)C=C3

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
AZD-0284
Cat. No.:
HY-120384
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AZD-0284

Cat. No.: HY-120384