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Reference Standards
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Reference Standards Related Products (11770)
Related Products (11770)
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Z-VAD-FMK (Standard)
0 ImagesCat. No.: HY-16658BRCAS No.: 161401-82-7Synonyms: Z-VAD(OH)-FMK (Standard)Z-VAD-FMK (Standard) is the analytical standard of Z-VAD-FMK (HY-16658B). This product is intended for research and analytical applications. Z-VAD-FMK is a pan-caspase inhibitor and also an ICE-like protease inhibitor, which inhibits apoptosis by preventing the processing of CPP32 to its active form. Z-VAD-FMK sensitivity varies primarily due to differential expression of receptor-interacting protein 1 (RIP1). Z-VAD-FMK limits the cryopreservation-induced apoptosis by reducing caspase-3 activity of in vitro produced bovine embryos. Z-VAD-FMK is immunosuppressive in vitro and inhibits T cell proliferation without blocKing the processing of caspase-8 and caspase-3. Z-VAD-FMK leads to a decrease in intracellular glutathione (GSH) with a concomitant increase in reactive oxygen species (ROS) levels in activated T cells. Z-VAD-FMK is due to oxidative stress via the depletion of GSH. Z-VAD-FMK can be used for the study of acute pancreatitis. -
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L-Thyroxine sodium salt pentahydrate (Standard)
0 ImagesSynonyms: Sodium levothyroxine pentahydrate (Standard)L-Thyroxine (sodium salt pentahydrate) (Standard) is the analytical standard of L-Thyroxine (sodium salt pentahydrate). This product is intended for research and analytical applications. L-Thyroxine sodium salt pentahydrate (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4). -
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Ledipasvir impurity 55 (Standard)
0 ImagesCat. No.: HY-Z0286RCAS No.: 1499193-60-02-Bromo-9,9-difluoro-7-iodo-9H-fluorene (Standard) is the analytical standard of 2-Bromo-9,9-difluoro-7-iodo-9H-fluorene. This product is intended for research and analytical applications. -
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- WM-8014 (Standard)
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Soraprazan (Standard)
0 ImagesCat. No.: HY-100414RCAS No.: 261944-46-1Synonyms: BYK61359 (Standard)Soraprazan (Standard) is the analytical standard of Soraprazan (HY-100414). This product is intended for research and analytical applications. Soraprazan (BYK61359) is a selective, reversible K-competitive inhibitor of the H,K-ATPase (Ki=6.4 nM), with an IC50 of 0.19 μM in gastric glands. Soraprazan binds to the H,K-ATPase with a Kd of 28.27 nM. Soraprazan shows immediate inhibition of acid secretion and is more than 2000-fold selective for H,K-ATPase over Na,K- and Ca-ATPases. -
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5'-N-Ethylcarboxamidoadenosine (Standard)
0 ImagesSynonyms: NECA (Standard)5'-N-Ethylcarboxamidoadenosine (Standard) is the analytical standard of 5'-N-Ethylcarboxamidoadenosine. This product is intended for research and analytical applications. 5'-N-Ethylcarboxamidoadenosine (NECA) is a nonselective adenosine receptor agonist. -
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- LM22B-10 (Standard)
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2-Methylheptanoic acid (Standard)
0 ImagesCat. No.: HY-W015664RCAS No.: 1188-02-92-Methylheptanoic acid (Standard) is the analytical standard of 2-Methylheptanoic acid (HY-W015664). This product is intended for research and analytical applications. 2-Methylheptanoic acid is a naturally occurring branched-chain medium-chain fatty acid with fumigant activity against Aspergillus flavus. 2-Methylheptanoic acid inhibits the growth of Aspergillus flavus and kills its spores via two modes of action, namely fumigation and direct contact, with its fumigant activity being stronger than its direct contact activity. 2-Methylheptanoic acid can be used in studies related to Aspergillus flavus infection. -
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- 4-Diethylaminobenzaldehyde (Standard)
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Simazine (Standard)
0 ImagesSimazine (Standard) is the analytical standard of Simazine (HY-B2046). This product is intended for research and analytical applications. Simazine is a triazine herbicide. Simazine is widely used in agriculture, potted plant and tree production. In addition, Simazine can induce the apoptosis of immune cells in the spleen of mice and inhibit the proliferation of B cells and T cells in mice. -
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Losmapimod (Standard)
0 ImagesSynonyms: GSK-AHAB (Standard); GW856553X (Standard); SB856553 (Standard)Losmapimod (GSK-AHAB; GW856553X) (Standard) is the analytical standard of Losmapimod (HY-10402). This product is intended for research and analytical applications. Losmapimod (GSK-AHAB; GW856553X) is an orally active p38α/β MAPK inhibitor, with pKi values of 8.1 and 7.6 for p38α and p38β, respectively. Losmapimod reduces DUX4 expression, thus exerting efficacy in facioscapulohumeral muscular dystrophy. By inhibiting MAPK/NF-κB, Losmapimod reduces apoptosis of epileptiform hippocampal neurons, and exhibits anti-allodynia and anti-hyperalgesic activities. Losmapimod blocks the entry and fusion of Lassa fever virus (LASV). Losmapimod overcomes tyrosine kinase inhibitor resistance in non-small cell lung cancer (NSCLC). Losmapimod inhibits myocardial senescence and inflammation, and possesses cardioprotective activity against cardiotoxicity. -
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Tiplaxtinin (Standard)
0 ImagesCat. No.: HY-15253RCAS No.: 393105-53-8Synonyms: PAI-039 (Standard); Tiplasinin (Standard)Tiplaxtinin (Standard) is the analytical standard of Tiplaxtinin (HY-15253). This product is intended for research and analytical applications. Tiplaxtinin is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 μM. -
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SU16f (Standard)
0 ImagesCat. No.: HY-108628RCAS No.: 251356-45-3SU16f (Standard) is the analytical standard of SU16f (HY-108628). This product is intended for research and analytical applications. SU16f is a potent and selective PDGFRβ inhibitor with IC50s of 10 nM, 140 nM, 2.29 μM for PDGFRβ, VEGF-R2, FGF-R1, respectively. Neutralization of PDGFRβ receptor by SU16f blocks the promoting role of GC-MSCs (gastric cancer-derived mesenchymal stem cells) conditioned medium in gastric cancer cell proliferation and migration. -
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Propetamphos (Standard)
0 ImagesCat. No.: HY-119525RCAS No.: 31218-83-4Propetamphos (Standard) is the analytical standard of Propetamphos. This product is intended for research and analytical applications. Propetamphos is an organophosphorus insecticide. Propetamphos causes cytotoxicity and oxidative stress. -
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Pixantrone (Standard)
0 ImagesSynonyms: BBR 2778 (Standard)Pixantrone (Standard) is the analytical standard of Pixantrone. This product is intended for research and analytical applications. Pixantrone (BBR 2778) dimaleate is a topoisomerase II inhibitor and DNA intercalator, with anti-tumor activity. -
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Varenicline Hydrochloride (Standard)
0 ImagesSynonyms: CP 526555 hydrochloride (Standard)Varenicline (Hydrochloride) (Standard) is the analytical standard of Varenicline (Hydrochloride). This product is intended for research and analytical applications. Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation. -
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Synta66 (Standard)
0 ImagesCat. No.: HY-111325RCAS No.: 835904-51-3Synta66 (Standard) is the analytical standard of Synta66 (HY-111325). This product is intended for research and analytical applications. Synta66 is an inhibitor of store-operated calcium entry channel Orai, which forms the pore of the CRAC channel, and used for the research of neurological disease. -
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Pencycuron (Standard)
0 ImagesCat. No.: HY-B2048RCAS No.: 66063-05-6Pencycuron (Standard) is the analytical standard of Pencycuron. This product is intended for research and analytical applications. Pencycuron is a benzoylurea fungicide. Pencycuron kills fungi by inhibiting the synthesis of fungal cell walls.Pencycuron can be used in research on the control of fungal diseases on crops, such as sheath blight, powdery mildew and late blight. -
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DL-Sulforaphane N-acetyl-L-cysteine (Standard)
0 ImagesCat. No.: HY-132242RCAS No.: 334829-66-2Synonyms: SFN-NAC (Standard)Pipemidic acid (trihydrate) (Standard) is the analytical standard of Pipemidic acid (trihydrate). This product is intended for research and analytical applications. Pipemidic acid trihydrate, a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid trihydrate inhibits DNA gyrase. Pipemidic acid trihydrate is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid trihydrate can be used for the research of intestinal, urinary, and biliary tract infections. -
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2-((Dimethylamino)methyl)cyclohexan-1-one hydrochloride (Standard)
0 ImagesCat. No.: HY-W010001RCAS No.: 42036-65-72-((Dimethylamino)methyl)cyclohexan-1-one hydrochloride (Standard) is the analytical standard of 2-((Dimethylamino)methyl)cyclohexan-1-one hydrochloride. This product is intended for research and analytical applications. -
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