120-21-8
120-21-8
Chemical Structure
4-Diethylaminobenzaldehyde
- CAS No.: 120-21-8
- Formula:C11H15NO
- Molecular Weight:177.24
IUPAC Name: 4-(diethylamino)benzaldehyde
InChIKey: MNFZZNNFORDXSV-UHFFFAOYSA-N
SMILES: O=CC1=CC=C(N(CC)CC)C=C1
Biological Activity: 4-Diethylaminobenzaldehyde is a reversible aldehyde dehydrogenases (ALDHs) inhibitor, with a Ki of 4 nM for ALDH1. 4-Diethylaminobenzaldehyde displays potent anti-androgenic effect (IC50= 1.71μM)[1][2].
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4-Diethylaminobenzaldehyde | 99.98% | 4-Diethylaminobenzaldehyde is a reversible aldehyde dehydrogenases (ALDHs) inhibitor, with a Ki of 4 nM for ALDH1. 4-Diethylaminobenzaldehyde displays potent anti-androgenic effect (IC50= 1.71μM). | ||||||||||||||||||||
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4-Diethylaminobenzaldehyde (Standard) | ≥98% | 4-Diethylaminobenzaldehyde is a reversible aldehyde dehydrogenases (ALDHs) inhibitor, with a Ki of 4 nM for ALDH1. 4-Diethylaminobenzaldehyde displays potent anti-androgenic effect (IC50= 1.71μM). | ||||||||||||||||||||
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References
- [1]. Luo M, et al. Diethylaminobenzaldehyde is a covalent, irreversible inactivator of ALDH7A1. ACS Chem Biol. 2015 Mar 20;10(3):693-7. [Content Brief]
- [2]. Araki N, et al. Screening for androgen receptor activities in 253 industrial chemicals by in vitro reporter gene assays using AR-EcoScreen cells. Toxicol In Vitro. 2005 Sep;19(6):831-42. [Content Brief]
