Reference Standards
Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.
-
Reference Standards Related Products (11772)
Related Products (11772)
-
L-Homocystine (Standard)
0 ImagesCat. No.: HY-W011690RCAS No.: 626-72-2L-Homocystine (Standard) is the analytical standard of L-Homocystine (HY-W011690). This product is intended for research and analytical applications. L-Homocystine is the oxidized member of the L-homocysteine. Homocysteine is a pro-thrombotic factor, vasodilation impairing agent, pro-inflammatory factor and endoplasmatic reticulum-stress inducer used to study cardiovascular disease mechanisms.
-
Obefazimod (Standard)
0 ImagesSynonyms: ABX464 (Standard)Obefazimod (Standard) is the analytical standard of Obefazimod (HY-100870). This product is intended for research and analytical applications. Obefazimod (ABX464) is a potent anti-HIV agent. Obefazimod inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) with an IC50 ranging between 0.1 μM and 0.5 μM.
-
2,4-D (Standard)
0 ImagesSynonyms: 2,4-Dichlorophenoxyacetic acid (Standard)2,4-D (Standard) is the analytical standard of 2,4-D (HY-18572). This product is intended for research and analytical applications. 2,4-D (2, 4-dichlorophenoxyacetic acid) is a selective herbicide that can be used for the control of broad-leaved weeds. 2,4-D can induce apoptosis. 2,4-D inhibits DNA and protein synthesis, thereby preventing normal plant growth and development.
-
Zerencotrep (Standard)
0 ImagesCat. No.: HY-101507RCAS No.: 1628287-16-0Synonyms: Pico145 (Standard); HC-608 (Standard)Zerencotrep (Standard) is the analytical standard of Zerencotrep (HY-101507). This product is intended for research and analytical applications. Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels, inhibits (-)-englerin A-activated TRPC4/TRPC5 channels, with IC50s of 0.349 and 1.3 nM in cells, and shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8.
-
5-Methoxytryptophol (Standard)
0 Images5-Methoxytryptophol (Standard) is the analytical standard of 5-Methoxytryptophol. This product is intended for research and analytical applications. 5-Methoxytryptophol is a 5-methoxyindole alcohol structurally homologous to Melatonin (HY-B0075). It is secreted by the mammalian pineal gland and exhibits an inverse circadian rhythm. 5-Methoxytryptophol regulates bone metabolism by activating the ERK1/2 pathway. It reduces the levels of pro-inflammatory cytokines TNF-α and IL-1β, as well as proteolytic enzymes MMP-1 and MMP-2, in serum and dental pulp tissues, thereby ameliorating acute pulpitis. 5-Methoxytryptophol induces rapid sleep in mice, while high doses cause respiratory depression and death. 5-Methoxytryptophol. 5-Methoxytryptophol can be used in studies related to acute pulpitis, hypnosis, and bone metabolism.
-
4-Bromo-2-fluoro-1,1'-biphenyl (Standard)
0 ImagesCat. No.: HY-W011919RCAS No.: 41604-19-7Synonyms: 4-Bromo-2-fluorobiphenyl (Standard)4-Bromo-2-fluoro-1,1'-biphenyl (Standard) is the analytical standard of 4-Bromo-2-fluoro-1,1'-biphenyl. This product is intended for research and analytical applications.
-
3,4-Methylenedioxycinnamic acid (Standard)
0 ImagesCat. No.: HY-W009993RCAS No.: 2373-80-03,4-Methylenedioxycinnamic acid (Standard) is the analytical standard of 3,4-Methylenedioxycinnamic acid (HY-W009993). This product is intended for research and analytical applications. 3,4-Methylenedioxycinnamic acid is an inhibitor of the 4-hydroxycinnamoyl-CoA ligase (4CL) with a Ki of 100 μM. 3,4-Methylenedioxycinnamic acid exhibits the Km value for the substrate ferulic acid of 4CL is 8.4 μM.3,4-Methylenedioxycinnamic acid increases the formation of soluble phenolics in particular of vanillic acid. 3,4-Methylenedioxycinnamic acid demonstrates larvicidal activity.
-
WAY-200070 (Standard)
0 ImagesCat. No.: HY-101271RCAS No.: 440122-66-7WAY-200070 (Standard) is the analytical standard of WAY-200070 (HY-101271). This product is intended for research and analytical applications. WAY-200070 is a selective estrogen receptor β (ERβ) agonist with an IC50 of 2.3 nM.
-
Donitriptan (Standard)
0 ImagesCat. No.: HY-106157RCAS No.: 170912-52-4Synonyms: F-11356 free base (Standard)Donitriptan (Standard) is the analytical standard of Donitriptan (HY-106157). This product is intended for research and analytical applications. Donitriptan is a potent, high efficacy agonist at 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively.
-
Lapachol (Standard)
0 ImagesLapachol (Standard) is the analytical standard of Lapachol. This product is intended for research and analytical applications. Lapachol, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity.
-
GSK126 (Standard)
0 ImagesCat. No.: HY-13470RCAS No.: 1346574-57-9Synonyms: GSK2816126A (Standard)
-
Zandelisib (Standard)
0 ImagesCat. No.: HY-109198RCAS No.: 1401436-95-0Synonyms: ME-401 (Standard); PWT-143 (Standard)Zandelisib (Standard) is the analytical standard of Zandelisib (HY-109198). This product is intended for research and analytical applications. Zandelisib (ME-401) is a selective, orally active, non-covalent inhibitor of PI3Kδ. Zandelisib can sustainably inhibit AKT phosphorylation and downstream signaling pathways. Zandelisib can be used in the study of malignancies such as relapsed/refractory B-cell lymphoma.
-
(R,S,R)-ML334 (Standard)
0 ImagesCat. No.: HY-110258BRCAS No.: 1432065-33-2Synonyms: (R,S,R)-LH601A (Standard)(R,S,R)-ML334 (Standard) is the analytical standard of (R,S,R)-ML334 (HY-110258B). This product is intended for research and analytical applications. (R,S,R)-ML334 is the isomer of ML334 (HY-110258), and can be used as an experimental control. ML334 is a potent, cell permeable activator of NRF2 by inhibition of Keap1-NRF2 protein-protein interaction. ML334 binds to Keap1 Kelch domain with a Kd of 1 μM. ML334 stimulates NRF2 expression and nuclear translocation and induces antioxidant response elements (ARE) activity.
-
Astragaloside I (Standard)
0 ImagesCat. No.: HY-N0432RCAS No.: 84680-75-1Synonyms: Astrasieversianin IV (Standard); Cyclosieversioside B (Standard)Astragaloside I (Standard) is the analytical standard of Astragaloside I. This product is intended for research and analytical applications. Astragaloside I, one of the main active ingredients in Astragalus membranaceus, has osteogenic properties. Astragaloside I stimulates osteoblast differentiation through the Wnt/β-catenin signaling pathway.
-
JNJ-47965567 (Standard)
0 ImagesCat. No.: HY-101418RCAS No.: 1428327-31-4JNJ-47965567 (Standard) is the analytical standard of JNJ-47965567 (HY-101418). This product is intended for research and analytical applications. JNJ-47965567 is a centrally permeable, high-affinity, selective P2X7 antagonist, with pKis of 7.9 and 8.7 for human and rat P2X7, respectively. JNJ-47965567 can be used to probe the role of central P2X7 in rodent models of CNS pathophysiology.
-
Dihydrosinapyl alcohol (Standard)
0 ImagesCat. No.: HY-W025371RCAS No.: 20736-25-8Dihydrosinapyl alcohol (Standard) is the analytical standard of Dihydrosinapyl alcohol (HY-W025371). This product is intended for research and analytical applications. Dihydrosinapyl alcohol, a natural product, can be obtained from lignocellulose by hydrogenation and hydrogenolysis.
-
Paliperidone palmitate (Standard)
0 ImagesSynonyms: 9-Hydroxyrisperidone palmitate (Standard)Paliperidone palmitate (Standard) is the analytical standard of Paliperidone palmitate. This product is intended for research and analytical applications. Paliperidone palmitate is an orally effective competitive antagonist of dopamine D2 receptors and 5-hydroxytryptamine 2A (5-HT2A) receptors that can cross the blood-brain barrier. Paliperidone palmitate competitively inhibits the effects of dopamine and 5-hydroxytryptamine by binding to dopamine D2 receptors and 5-HT2A receptors, regulating the balance of the neurotransmitter system and thus exerting antipsychotic activity. Paliperidone palmitate is mainly used in the research field of schizophrenia.
-
Aphidicolin (Standard)
0 ImagesCat. No.: HY-N6733RCAS No.: 38966-21-1Aphidicolin (Standard) is the analytical standard of Aphidicolin. This product is intended for research and analytical applications. Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering DNA polymerase activity. Aphidicolin is an antibiotic produced by mold Cephalosporium aphidicola, inhibits cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. Aphidicolin exhibits anti-orthopoxvirus activity and potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line.
-
6-Aminonicotinamide (Standard)
0 Images6-Aminonicotinamide, a potent antimetabolite of nicotinamide, is competitive NADP+-dependent enzyme glucose-6-phosphate dehydrogenase (G6PD) inhibitor (Ki=0.46 μM). 6-Aminonicotinamide resultis ATP depletion and synergizes with DNA-crosslinking chemotherapy agents, such as Cisplatin (HY-17394), in killing cancer cells.
-
5,6-trans-Vitamin D3 (Standard)
0 ImagesSynonyms: 5,6-trans-Cholecalciferol (Standard); 5,6-trans-Colecalciferol (Standard); Cholecalciferol EP Impurity A (Standard)5,6-trans-Vitamin D3 (Standard) is the analytical standard of 5,6-trans-Vitamin D3. This product is intended for research and analytical applications. 5,6-trans-Vitamin D3 (5,6-trans-Cholecalciferol;5,6-trans-Colecalciferol) is a photoproduct of vitamin D3. Vitamin D3 is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.
