2373-80-0
2373-80-0
Chemical Structure
3,4-Methylenedioxycinnamic acid
- CAS No.: 2373-80-0
- Formula:C10H8O4
- Molecular Weight:192.17
IUPAC Name: (E)-3-(benzo[d][1,3]dioxol-5-yl)acrylic acid
InChIKey: QFQYZMGOKIROEC-DUXPYHPUSA-N
SMILES: O=C(O)/C=C/C1=CC=C(OCO2)C2=C1
Biological Activity: 3,4-Methylenedioxycinnamic acid is an inhibitor of the 4-hydroxycinnamoyl-CoA ligase (4CL) with a Ki of 100 μM. 3,4-Methylenedioxycinnamic acid exhibits the Km value for the substrate ferulic acid of 4CL is 8.4 μM.3,4-Methylenedioxycinnamic acid increases the formation of soluble phenolics in particular of vanillic acid. 3,4-Methylenedioxycinnamic acid demonstrates larvicidal activity[1][2].
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3,4-Methylenedioxycinnamic acid | 99.70% | 3,4-Methylenedioxycinnamic acid is an inhibitor of the 4-hydroxycinnamoyl-CoA ligase (4CL) with a Ki of 100 μM. 3,4-Methylenedioxycinnamic acid exhibits the Km value for the substrate ferulic acid of 4CL is 8.4 μM.3,4-Methylenedioxycinnamic acid increases the formation of soluble phenolics in particular of vanillic acid. 3,4-Methylenedioxycinnamic acid demonstrates larvicidal activity. | ||||||||||||||||||||
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3,4-Methylenedioxycinnamic acid (Standard) | ≥98% | 3,4-Methylenedioxycinnamic acid (Standard) is the analytical standard of 3,4-Methylenedioxycinnamic acid (HY-W009993). This product is intended for research and analytical applications. 3,4-Methylenedioxycinnamic acid is an inhibitor of the 4-hydroxycinnamoyl-CoA ligase (4CL) with a Ki of 100 μM. 3,4-Methylenedioxycinnamic acid exhibits the Km value for the substrate ferulic acid of 4CL is 8.4 μM.3,4-Methylenedioxycinnamic acid increases the formation of soluble phenolics in particular of vanillic acid. 3,4-Methylenedioxycinnamic acid demonstrates larvicidal activity. | ||||||||||||||||||||
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References
- [1]. Funk C, Brodelius PE. Phenylpropanoid Metabolism in Suspension Cultures of Vanilla planifolia Andr. : II. Effects of Precursor Feeding and Metabolic Inhibitors. Plant Physiol. 1990 Sep;94(1):95-101. [Content Brief]
- [2]. Silva MSL, et al. Biological evaluation of 1,3-benzodioxole acids points to 3,4-(methylenedioxy) cinnamic acid as a potential larvicide against Aedes aegypti (Diptera: Culicidae). Exp Parasitol. 2024 Jan;256:108657. [Content Brief]
