Urocortin, human
Based on 1 Customer Validation
Urocortin, human, a 40-aa neuropeptide, acts as an agonist of endogenous CRF receptor, with Kis of 0.4, 0.3, and 0.5 nM for hCRF1, rCRF2α and mCRF2β, respectively.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.85%
- CAS 番号: 176591-49-4
- 分子式: C204H337N63O64
- 分子量:4696.24
-
保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
-
HY-P0086
Corticotropin-releasing factor (human)CRFR Modulator -
HY-P1752
Urocortin II, humanCRFR Agonist -
HY-P0257
AstressinCRF Antagonist -
HY-P1296
Urocortin, ratCRFR Agonist -
HY-14130
CP 376395CRF1 Receptor Antagonist -
HY-103377
Antalarmin hydrochlorideCRHR1 Antagonist -
HY-12129
CP 154526 hydrochlorideCRF1 Antagonist -
HY-P1294
α-Helical CRF(9-41)CRFR Modulator -
HY-14875
VerucerfontCRFR Antagonist -
HY-P0276
GIP, humanInsulin Secretion Stimulator -
HY-12127
PexacerfontCRFR Antagonist -
HY-124475
AntalarminCRHR1 Antagonist
生物活性
製品説明
IC50 & Target
Ki: 0.4 nM (hCRF1, cell assay), 0.3 nM (rCRF2α, cell assay), and 0.5 nM (mCRF2β, cell assay)[1]
体外実験
Urocortin, human is an agonist of CRF receptor, with Kis of 0.4, 0.3, and 0.5 nM for human CRF1, rat CRF2α and mouse CRF2β receptors in cell assay, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 176591-49-4
-
性状 Solid
-
分子量 4696.24
-
分子式 C204H337N63O64
-
Color White to off-white
-
別名
Urocortin (human); ウロコルチン ヒト; Human urocortin; Human urocortin 1; Human urocortin I
-
配列
Asp-Asn-Pro-Ser-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH2
-
シーケンスの短縮
DNPSLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSV-NH2
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
1 M Acetic acid : 100 mg/mL (21.29 mM; Need ultrasonic)
DMSO : 2 mg/mL (0.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (285 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| 1 M Acetic acid | 1 mM | 0.2129 mL | 1.0647 mL | 2.1294 mL | 5.3234 mL |
| 5 mM | 0.0426 mL | 0.2129 mL | 0.4259 mL | 1.0647 mL | |
| 10 mM | 0.0213 mL | 0.1065 mL | 0.2129 mL | 0.5323 mL | |
| 15 mM | 0.0142 mL | 0.0710 mL | 0.1420 mL | 0.3549 mL | |
| 20 mM | 0.0106 mL | 0.0532 mL | 0.1065 mL | 0.2662 mL |
Urocortin, human 関連分類
HY-P1295 関連分類
Powered by Bioz