1. Metabolic Enzyme/Protease
  2. Angiotensin-converting Enzyme (ACE)
  3. Utibapril

Utibapril (Synonyms: FPL 63547)

Cat. No.: HY-101681
Handling Instructions

Utibapril is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activities.

For research use only. We do not sell to patients.

Utibapril Chemical Structure

Utibapril Chemical Structure

CAS No. : 109683-61-6

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Description

Utibapril is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activities.

In Vivo

Utibapril significantly inhibits plasma, renal, and vascular ACE but not ventricular ACE activity. Utibapril (2 μg/kg/day) significantly inhibits vascular ACE activity, and Utibapril (250 μg/kg/day) results in a significant inhibition of plasma ACE. Furthermore, angiotensin I-induced decreases in coronary flow in the isolated heart are significantly inhibited after treatment with the higher doses of utibapril[1]. FPL 63547 is rapidly and extensively excreted as the diacid in the bile but appeared in the urine in negligible amounts[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

449.56

Formula

C₂₂H₃₁N₃O₅S

CAS No.

109683-61-6

SMILES

O=C([[email protected]@H]1SC(C(C)(C)C)=NN1C([[email protected]@H](N[[email protected]](C(OCC)=O)CCC2=CC=CC=C2)C)=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

UtibaprilFPL 63547FPL63547FPL-63547Angiotensin-converting Enzyme (ACE)Inhibitorinhibitorinhibit

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Utibapril
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HY-101681
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