β-Amyloid (1-15)
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β-Amyloid (1-15) is a fragment of β-Amyloid peptide. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 183745-81-5
- 分子式: C78H107N25O27
- 分子量:1826.84
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* The compound is unstable in solutions, freshly prepared is recommended.
生物活性
Amyloid-β[1]
β-Amyloid (1-15) is produced by concerted β- and α-secretase cleavage of amyloid-β protein precursor (AβPP). β-Amyloid (1-15) seems to be a sensitive acute pharmacodynamic biomarker for γ-secretase inhibition and may have several advantages compared to measuring longer CSF Aβ species. [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 183745-81-5
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性状 Solid
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分子量 1826.84
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分子式 C78H107N25O27
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Color White to off-white
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別名
Amyloid β-Protein (1-15)
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配列
Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln
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シーケンスの短縮
DAEFRHDSGYEVHHQ
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * The compound is unstable in solutions, freshly prepared is recommended.
溶剤 & 溶解度
H2O : 50 mg/mL (27.37 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (252 KB)
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- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.5474 mL | 2.7370 mL | 5.4739 mL | 13.6848 mL |
| 5 mM | 0.1095 mL | 0.5474 mL | 1.0948 mL | 2.7370 mL | |
| 10 mM | 0.0547 mL | 0.2737 mL | 0.5474 mL | 1.3685 mL | |
| 15 mM | 0.0365 mL | 0.1825 mL | 0.3649 mL | 0.9123 mL | |
| 20 mM | 0.0274 mL | 0.1368 mL | 0.2737 mL | 0.6842 mL | |
| 25 mM | 0.0219 mL | 0.1095 mL | 0.2190 mL | 0.5474 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.