β-Amyloid (1-15)
Based on 1 Customer Validation
β-Amyloid (1-15) is a fragment of β-Amyloid peptide. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients.
For research use only. We do not sell to patients.
- CAS No.: 183745-81-5
- Formula: C78H107N25O27
- Molecular Weight:1826.84
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* The compound is unstable in solutions, freshly prepared is recommended.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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HY-P0128
β-Amyloid (25-35)Amyloid β Peptide -
HY-P0128A
β-Amyloid (25-35), HFIP-treatedAmyloid β Peptide -
HY-13027
DAPTγ-secretase Inhibitor -
HY-P1363A
β-Amyloid (1-42), humanAmyloid β Peptide -
HY-P1363B
β-Amyloid (1-42), human, HFIP-treatedβ-Amyloid (1-42) Peptide -
HY-P1388
β-Amyloid (1-42), (rat/mouse)β-Amyloid (1-42) Peptide -
HY-P1061
ColivelinNeuroprotectant/STAT3 Activator -
HY-P1051
β-Amyloid (12-28)Amyloid Peptide -
HY-N0009
GeniposideInfluenza Virus Inhibitor -
HY-19370
FPS-ZM1Amyloid-β Inhibitor -
HY-13027G
DAPT (GMP)γ-Secretase Inhibitor -
HY-P1362
β-Amyloid (42-1), humanInactive Form of Aβ(1-42)
Biological Activity
Description
IC50 & Target
Amyloid-β[1]
In Vitro
β-Amyloid (1-15) is produced by concerted β- and α-secretase cleavage of amyloid-β protein precursor (AβPP). β-Amyloid (1-15) seems to be a sensitive acute pharmacodynamic biomarker for γ-secretase inhibition and may have several advantages compared to measuring longer CSF Aβ species. [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 183745-81-5
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Appearance Solid
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Molecular Weight 1826.84
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Formula C78H107N25O27
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Color White to off-white
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Synonyms
Amyloid β-Protein (1-15)
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Sequence
Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln
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Sequence Shortening
DAEFRHDSGYEVHHQ
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * The compound is unstable in solutions, freshly prepared is recommended.
Solvent & Solubility
In Vitro:
H2O : 50 mg/mL (27.37 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Hot Topics
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All
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Topics
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Most Recent
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Topics Cellular Senescence, Aging & Age-Related Diseases
Cellular senescence refers to the irreversible growth arrest that occurs in cells after a period of proliferation in vitro, following sublethal stress or oncogene expression.
2025-11-20
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.5474 mL | 2.7370 mL | 5.4739 mL | 13.6848 mL |
| 5 mM | 0.1095 mL | 0.5474 mL | 1.0948 mL | 2.7370 mL | |
| 10 mM | 0.0547 mL | 0.2737 mL | 0.5474 mL | 1.3685 mL | |
| 15 mM | 0.0365 mL | 0.1825 mL | 0.3649 mL | 0.9123 mL | |
| 20 mM | 0.0274 mL | 0.1368 mL | 0.2737 mL | 0.6842 mL | |
| 25 mM | 0.0219 mL | 0.1095 mL | 0.2190 mL | 0.5474 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
β-Amyloid (1-15) Related Classifications
HY-P1046 Related Classifications
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