AChE-IN-37
Based on 1 Customer Validation
AChE-IN-37 (compound A2) is anacetylcholinesterase inhibitorswith an IC50 of 0.23 μM. AChE-IN-37 effects ROS levels and gene expression of NRF2.
For research use only. We do not sell to patients.
- Purity: 99.77%
- CAS No.: 2978753-64-7
- Formula: C21H12ClNO7S
- Molecular Weight:457.84
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
IC50=0.23 μM (acetylcholinesterase)[1]
Chemical Information
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CAS No. 2978753-64-7
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Appearance Solid
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Molecular Weight 457.84
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Formula C21H12ClNO7S
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Color Light yellow to yellow
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SMILES
O=S(C1=CC=C([N+]([O-])=O)C=C1)(OC2=CC=C3C(/C(OC3=C2)=C/C4=CC=C(Cl)C=C4)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 31.25 mg/mL (68.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1842 mL | 10.9208 mL | 21.8417 mL | 54.6042 mL |
| 5 mM | 0.4368 mL | 2.1842 mL | 4.3683 mL | 10.9208 mL | |
| 10 mM | 0.2184 mL | 1.0921 mL | 2.1842 mL | 5.4604 mL | |
| 15 mM | 0.1456 mL | 0.7281 mL | 1.4561 mL | 3.6403 mL | |
| 20 mM | 0.1092 mL | 0.5460 mL | 1.0921 mL | 2.7302 mL | |
| 25 mM | 0.0874 mL | 0.4368 mL | 0.8737 mL | 2.1842 mL | |
| 30 mM | 0.0728 mL | 0.3640 mL | 0.7281 mL | 1.8201 mL | |
| 40 mM | 0.0546 mL | 0.2730 mL | 0.5460 mL | 1.3651 mL | |
| 50 mM | 0.0437 mL | 0.2184 mL | 0.4368 mL | 1.0921 mL | |
| 60 mM | 0.0364 mL | 0.1820 mL | 0.3640 mL | 0.9101 mL |