Aciculatin
Aciculatin is a compound with cytotoxic, anti-inflammatory and anti-arthritic activities, and its synthetic route including specific chemical reaction steps was determined through the first total synthesis.
For research use only. We do not sell to patients.
- CAS No.: 134044-97-6
- Formula: C22H22O8
- Molecular Weight:414.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | IC50 |
2.65 μM
Compound: aciculatin
|
Cytotoxicity against human CEM cells after 48 hrs by alamar blue assay
Cytotoxicity against human CEM cells after 48 hrs by alamar blue assay
|
[PMID: 22272829] |
| HT-29 | IC50 |
25.98 μM
Compound: aciculatin
|
Cytotoxicity against human HT-29 cells after 48 hrs by alamar blue assay
Cytotoxicity against human HT-29 cells after 48 hrs by alamar blue assay
|
[PMID: 22272829] |
| MCF7 | IC50 |
3.16 μM
Compound: aciculatin
|
Cytotoxicity against human MCF7 cells after 48 hrs by alamar blue assay
Cytotoxicity against human MCF7 cells after 48 hrs by alamar blue assay
|
[PMID: 22272829] |
| NCI-H460 | IC50 |
46.94 μM
Compound: aciculatin
|
Cytotoxicity against human NCI-H460 cells after 48 hrs by alamar blue assay
Cytotoxicity against human NCI-H460 cells after 48 hrs by alamar blue assay
|
[PMID: 22272829] |
Chemical Information
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CAS No. 134044-97-6
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Molecular Weight 414.41
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Formula C22H22O8
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SMILES
COC1=CC(O)=C(C(C=C(C2=CC=C(C=C2)O)O3)=O)C3=C1[C@H]4C[C@@H]([C@@H]([C@H](O4)C)O)O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)