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AHR antagonist 8

AHR antagonist 8 (compound SG-02) is a regulator of utrophin, a homolog of dystrophin, and an AhR antagonist (Kd: 41.68 nM). Studies have shown that 800 nM of AHR antagonist 8 can upregulate utrophin by 2.7 times. AHR antagonist 8 also stimulates increased MyHC expression, suggesting that it has the potential to enhance myogenesis. After ADME evaluation, AHR antagonist 8 also has a certain oral bioavailability.

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  • CAS No.: 3052113-26-2
  • Formula: C16H14FN3O2S
  • Molecular Weight:331.36
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • AHR antagonist 8 Chemical Structure
    AHR antagonist 8 Chemical Structure
CAS No.: 3052113-26-2
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  • AHR antagonist 8