AKT-IN-14
AKT-IN-14 (Example 2) is a potent AKTinhibitor with the IC50 values of <0.01 nM, 1.06 nM and 0.66 nM for AKT1, AKT2, AKT3, respectively. AKT-IN-14 can be used in cancer research.
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- No. CAS: 2781918-35-0
- Fòrmula: C22H22BrClF2N4OS
- Peso molecular:543.86
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| N2a | IC50 |
<0.63 μM
Compound: B6
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Antiproliferative activity against mouse Neuro2a cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
Antiproliferative activity against mouse Neuro2a cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
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[PMID: 37749892] |
Chemical Information
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No. CAS 2781918-35-0
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Peso molecular 543.86
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Fòrmula C22H22BrClF2N4OS
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SMILES
BrC1=C2C3=C(CCCN2N=C1)SC(C(N[C@H]4[C@H](C5=CC(F)=C(C=C5)F)CCNC4)=O)=C3.[H]Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AKT-IN-14 Related Classifications
HY-153640 Related Classifications
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