AKT-IN-14
AKT-IN-14 (Example 2) is a potent AKTinhibitor with the IC50 values of <0.01 nM, 1.06 nM and 0.66 nM for AKT1, AKT2, AKT3, respectively. AKT-IN-14 can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2781918-35-0
- Formula: C22H22BrClF2N4OS
- Molecular Weight:543.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| N2a | IC50 |
<0.63 μM
Compound: B6
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Antiproliferative activity against mouse Neuro2a cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
Antiproliferative activity against mouse Neuro2a cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
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[PMID: 37749892] |
Chemical Information
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CAS No. 2781918-35-0
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Molecular Weight 543.86
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Formula C22H22BrClF2N4OS
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SMILES
BrC1=C2C3=C(CCCN2N=C1)SC(C(N[C@H]4[C@H](C5=CC(F)=C(C=C5)F)CCNC4)=O)=C3.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AKT-IN-14 Related Classifications
HY-153640 Related Classifications
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