1. Metabolic Enzyme/Protease
  2. Neprilysin Angiotensin-converting Enzyme (ACE)
  3. Alatrioprilat

Alatrioprilat is an orally active inhibitor of angiotensin-converting enzyme (ACE) (IC50=19.6 nM; Ki=9.8 nM) and enkephailnase (IC50=6.1 nM; Ki=5.1 nM). Alatrioprilat plays a key role in the metabolism of hormonal peptides through the degradation of nitric oxide and atrial natriuretic factor (ANF). Alatrioprilat can be used in the study of cardiovascular diseases.

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Alatrioprilat Chemical Structure

Alatrioprilat Chemical Structure

CAS No. : 135038-59-4

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Description

Alatrioprilat is an orally active inhibitor of angiotensin-converting enzyme (ACE) (IC50=19.6 nM; Ki=9.8 nM) and enkephailnase (IC50=6.1 nM; Ki=5.1 nM). Alatrioprilat plays a key role in the metabolism of hormonal peptides through the degradation of nitric oxide and atrial natriuretic factor (ANF). Alatrioprilat can be used in the study of cardiovascular diseases[1].

Molecular Weight

311.35

Formula

C14H17NO5S

CAS No.
SMILES

OC([C@H](C)NC([C@@H](CS)CC1=CC=C(OCO2)C2=C1)=O)=O

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Alatrioprilat
Cat. No.:
HY-117607
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