2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Ald-Ph-PEG4-bis-PEG3-methyltetrazine

Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

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Ald-Ph-PEG4-bis-PEG3-methyltetrazine

Ald-Ph-PEG4-bis-PEG3-methyltetrazine Chemische Struktur

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Ald-Ph-PEG4-bis-PEG3-methyltetrazine Related Antibodies

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Beschreibung

Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Ald-Ph-PEG4-bis-PEG3-methyltetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

IC50 & Target

Cleavable Linker

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Ald-Ph-PEG4-bis-PEG3-methyltetrazine Related Antibodies
Molekulargewicht

1387.53

Formel

C66H94N14O19
SMILES

O=C(CCOCCOCCOCCOCCNC(C1=CC=C(C=O)C=C1)=O)NC(COCCC(NCCOCCOCCOCCNC(CC2=CC=C(C3=NN=C(C)N=N3)C=C2)=O)=O)COCCC(NCCOCCOCCOCCNC(CC4=CC=C(C5=NN=C(C)N=N5)C=C4)=O)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
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Ald-Ph-PEG4-bis-PEG3-methyltetrazine Related Classifications

  • Molaritätsrechner

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Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ald-Ph-PEG4-bis-PEG3-methyltetrazineADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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