2. Metabolic Enzyme/Protease
  3. FXR
  4. Alismanol M

Alismanol M is a farnesoid X receptor (FXR) agonist with an EC50 value of 50.25 μM. Alismanol M is a protostane-type triterpenoid that can be isolated from the rhizome of Alisma orientale. Alismanol M can be used for the research of cholestasis and nonalcoholic steatohepatitis.

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Alismanol M

Alismanol M 화학구조

CAS No. : 2408810-59-1

사이즈 가격 재고 수량
1 mg 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
5 mg 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
10 mg   견적 받기  
50 mg   견적 받기  
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Alismanol M Related Antibodies

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제품 설명

Alismanol M is a farnesoid X receptor (FXR) agonist with an EC50 value of 50.25 μM. Alismanol M is a protostane-type triterpenoid that can be isolated from the rhizome of Alisma orientale. Alismanol M can be used for the research of cholestasis and nonalcoholic steatohepatitis[1].

Cellular Effect
Cell Line Type Value Description References
HepG2 EC50
50.25 μM
Compound: 37
Transactivation of FXR (unknown origin) transfected in HepG2 cells co-expressing pBSEP/pGL4.74 incubated for 24 hrs by luciferase reporter gene assay
Transactivation of FXR (unknown origin) transfected in HepG2 cells co-expressing pBSEP/pGL4.74 incubated for 24 hrs by luciferase reporter gene assay
[PMID: 31494470]
분자량

504.70

화학식

C30H48O6
CAS No.
SMILES

C[C@@]12[C@@]3(C([C@](O)(CC3)[C@H](C)C[C@H](O)[C@@H](O)C(C)(O)C)=CC([C@@]1([H])[C@@]4([C@@](C(C)(C(CC4)=O)C)([H])CC2)C)=O)C
Structure Classification
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
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Alismanol M Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Alismanol M2408810-59-1FXRNR1H4triterpenoidrhizomeAlisma orientalecholestasisnonalcoholic steatohepatitisInhibitorinhibitorinhibit

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상품명:
Alismanol M
Cat. No.:
HY-N10640
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