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Cat. No.: HY-185003

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α1A-AR ligand-1

α1A-AR ligand-1 (Compound 3) is an α1A-AR ligand that can be used to synthesize PROTACs, such as α1A-AR Degrader 9c (HY-147100).

For research use only. We do not sell to patients.

CAS No.: 1571081-31-6
Formula: C₁₇H₁₉N₅O₃
Molecular Weight:341.36

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

α1A-AR ligand-1 Chemical Structure

CAS No.: 1571081-31-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

α1A-AR ligand-1 (Compound 3) is an α1A-AR ligand that can be used to synthesize PROTACs, such as α1A-AR Degrader 9c (HY-147100)^[1].

IC₅₀ & Target^[1]

α1A-adrenergic receptor

All Adrenergic Receptor Isoforms :

Chemical Information

CAS No. 1571081-31-6
Molecular Weight 341.36
Formula C₁₇H₁₉N₅O₃
SMILES

O=C(C#C)N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Li Z, et al. First small-molecule PROTACs for G protein-coupled receptors: inducing α1A-adrenergic receptor degradation. Acta Pharm Sin B. 2020 Sep;10(9):1669-1679. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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α1A-AR ligand-1

All Adrenergic Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

α1A-AR ligand-1 Related Classifications

HY-185003 Related Classifications