α-Synuclein-IN-18
α-Synuclein-IN-18 (Compound Mol D) is an inhibitor of the autocatalytic proliferation of α-Synuclein aggregate. α-Synuclein-IN-18 can specifically bind to the conserved binding pocket on the surface of α-synuclein fibrils. α-Synuclein-IN-18 can delay the aggregation process of α-synuclein, extend the aggregation T1/2 by three times. α-Synuclein-IN-18 can reduce the generation flux of α-synuclein toxic oligomers, thereby alleviating the neurotoxicity. α-Synuclein-IN-18 can be used for research of Parkinson’sdisease.
For research use only. We do not sell to patients.
- CAS No.: 1394328-54-1
- Formula: C16H16N4O2
- Molecular Weight:296.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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All α-synuclein Isoforms
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Biological Activity
Chemical Information
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CAS No. 1394328-54-1
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Molecular Weight 296.32
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Formula C16H16N4O2
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SMILES
O=C(C1NCCC2=C1N=C(C3=CNC4=C3C=CC=C4C)N2)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
α-Synuclein-IN-18 Related Classifications
HY-178276 Related Classifications
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