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Cat. No.: HY-W288025

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ALXR-agonist-6

ALXR-agonist-6 (compound 36) is an ALXR agonist with the EC₅₀ values of >10 μM for Ca²⁺ flux in CHO recombinant cells co-expressing hFPRL1.

For research use only. We do not sell to patients.

CAS No.: 325850-26-8
Formula: C₁₈H₁₇ClN₄O₂
Molecular Weight:356.81

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

ALXR-agonist-6 Chemical Structure

CAS No.: 325850-26-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

ALXR-agonist-6 (compound 36) is an ALXR agonist with the EC₅₀ values of >10 μM for Ca²⁺ flux in CHO recombinant cells co-expressing hFPRL1^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	EC₅₀	>10 μM Compound: 36	Activity at human FPRL1-mediated calcium mobilization in CHO cells Activity at human FPRL1-mediated calcium mobilization in CHO cells	[PMID: 16697190]

Chemical Information

CAS No. 325850-26-8
Molecular Weight 356.81
Formula C₁₈H₁₇ClN₄O₂
SMILES

CC1=C(C(N(C2=CC=CC=C2)N1C)=O)NC(NC3=CC=CC(Cl)=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Ca²⁺ Staining Technique
Ca²⁺ staining is an experimental technique that utilizes specific fluorescent probes (such as Fluo-4 AM, Fura-2, etc.) to qualitatively or quantitatively detect dynamic changes in intracellular Ca²⁺ concentrations; this is achieved by monitoring the changes in fluorescent signals generated when these probes bind to free intracellular calcium ions. The underlying principle relies primarily on the presence of chelating groups within the probe's molecular structure that possess high affinity for calcium ions.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bürli RW, et al. Potent hFPRL1 (ALXR) agonists as potential anti-inflammatory agents. Bioorg Med Chem Lett. 2006;16(14):3713-3718. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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