Anti-CDCP1/CD318 Antibody (38 E11)  (Synonyms: 38 E11)

The Anti-CDCP1/CD318 Antibody (38 E11) is a CHO-expressed human antibody targeting CDCP1/CD318. The Anti-CDCP1/CD318 Antibody (38 E11) contains a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-CDCP1/CD318 Antibody (38 E11) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

Human IgG1 kappa

Human IgG1 kappa, Isotype Control

Human

CDCP1/CD318

Anti-CDCP1/CD318 Antibody (38 E11) is an essential tool for investigating Src-dependent signaling, tumor cell survival, and distal metastasis mechanisms, aiming to downregulate downstream oncogenic signaling cascades by blocking CDCP1 phosphorylation or inducing its internalization.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

64866  [NCBI]

Q9H5V8

ELISA, FACS, Functional assay

Unconjugated

The product can be reconstituted/diluted with sterile PBS or saline.

146 kDa

Liquid

Colorless to light yellow

Shipping with dry ice.

Please refer to the lot-specific COA for specific buffer information.

Please store the product under the recommended conditions in the Certificate of Analysis.

• 
  Flow cytometric analysis of 1×10⁶ MCF-7 cells labelling CDCP1 (red) with Anti-CDCP1/CD318 Antibody (38 E11) (HY-P990361). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).