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Anti-inflammatory agent 34 (Compound IVf) is an orally active anti-inflammatory and analgesic agent.

For research use only. We do not sell to patients.

Anti-inflammatory agent 34 Chemical Structure

Anti-inflammatory agent 34 Chemical Structure

CAS No. : 867301-81-3

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Based on 1 publication(s) in Google Scholar

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Description

Anti-inflammatory agent 34 (Compound IVf) is an orally active anti-inflammatory and analgesic agent[1].

In Vivo

Anti-inflammatory agent 34 (Compound IVf) (200mg/kg; p.o.; single dose) shows inhibitory activity on carrageenan induced rat paw edema, and shows analgesic activity in mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male albino rats, carrageenan-induced rat paw edema assay model[1]
Dosage: 200 mg/kg
Administration: Oral, single dose
Result: Showed 55.7 ± 0.019% inhibition on carrageenan induced rat paw edema at the 3rd h.
Animal Model: Albino mice, acetic acid induced writhing method[1]
Dosage: 200 mg/kg
Administration: Oral, single dose
Result: Showed 48.1% analgesic activity.
Molecular Weight

324.29

Formula

C17H12N2O5
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(NC1=CC=C(C(O2)=C1)C(C)=CC2=O)C3=CC=C([N+]([O-])=O)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMF : 1.85 mg/mL (5.70 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0837 mL 15.4183 mL 30.8366 mL
5 mM 0.6167 mL 3.0837 mL 6.1673 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMF 1 mM 3.0837 mL 15.4183 mL 30.8366 mL 77.0915 mL
5 mM 0.6167 mL 3.0837 mL 6.1673 mL 15.4183 mL
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Anti-inflammatory agent 34 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-inflammatory agent 34867301-81-3Othersorally activealbino ratsalbino miceanalgesic activityanti-inflammatoryInhibitorinhibitorinhibit

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