Anti-inflammatory agent 34
Based on 1 Customer Validation
Anti-inflammatory agent 34 (Compound IVf) is an orally active anti-inflammatory and analgesic agent.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.13%
- No. CAS: 867301-81-3
- Fòrmula: C17H12N2O5
- Peso molecular:324.29
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Actividad biológica
Descripciòn
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male albino rats, carrageenan-induced rat paw edema assay model[1]
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Dosage:200 mg/kg
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Administration:Oral, single dose
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Result:Showed 55.7 ± 0.019% inhibition on carrageenan induced rat paw edema at the 3rd h.
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Animal Model:Albino mice, acetic acid induced writhing method[1]
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Dosage:200 mg/kg
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Administration:Oral, single dose
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Result:Showed 48.1% analgesic activity.
Chemical Information
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No. CAS 867301-81-3
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Appearance Solid
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Peso molecular 324.29
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Fòrmula C17H12N2O5
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Color Off-white to light yellow
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SMILES
O=C(NC1=CC=C(C(O2)=C1)C(C)=CC2=O)C3=CC=C([N+]([O-])=O)C=C3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 2 mg/mL (6.17 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
DMF : 1.85 mg/mL (5.70 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Pureza y Documentación
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Ficha de datos (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMF / DMSO | 1 mM | 3.0837 mL | 15.4183 mL | 30.8366 mL | 77.0915 mL |
| 5 mM | 0.6167 mL | 3.0837 mL | 6.1673 mL | 15.4183 mL |