1. Anti-infection
  2. Bacterial
  3. Anti-MRSA agent 24

Anti-MRSA agent 24 (compound 6K) is an antimicrobial agent that targets Staphylococcus aureus (MRSA), especially penicillin-resistant Staphylococcus aureus.

For research use only. We do not sell to patients.

Anti-MRSA agent 24

Anti-MRSA agent 24 Chemical Structure

CAS No. : 2379890-92-1

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Description

Anti-MRSA agent 24 (compound 6K) is an antimicrobial agent that targets Staphylococcus aureus (MRSA), especially penicillin-resistant Staphylococcus aureus[1].

Cellular Effect
Cell Line Type Value Description References
CHO-K1 IC50
6.9 μM
Compound: 6u
Cytotoxicity against CHOK1 cells assessed as reduction in cell viability
Cytotoxicity against CHOK1 cells assessed as reduction in cell viability
[PMID: 31624041]
HFL1 IC50
15.6 μM
Compound: 6u
Cytotoxicity against human HFL1 cells assessed as reduction in cell viability
Cytotoxicity against human HFL1 cells assessed as reduction in cell viability
[PMID: 31624041]
L929 IC50
15.8 μM
Compound: 6u
Cytotoxicity against mouse L929 cells assessed as reduction in cell viability
Cytotoxicity against mouse L929 cells assessed as reduction in cell viability
[PMID: 31624041]
NIH3T3 IC50
65.6 μM
Compound: 6u
Cytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability
Cytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability
[PMID: 31624041]
Vero CC50
> 25 μM
Compound: 6u
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability
[PMID: 31624041]
Vero IC50
0.086 μM
Compound: 6u
Antiviral activity against MERS-CoV KOR/KNIH/002_05_2015 infected in African green monkey Vero cells expressing viral spike protein by immunofluorescence assay
Antiviral activity against MERS-CoV KOR/KNIH/002_05_2015 infected in African green monkey Vero cells expressing viral spike protein by immunofluorescence assay
[PMID: 31624041]
Molecular Weight

396.31

Formula

C19H13F5N2O2

CAS No.
SMILES

FC1=CC(F)=C(NC(NC2=CC=C(F)C(F)=C2F)=C(C(C(C)C)=O)C3=O)C3=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Anti-MRSA agent 24 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Anti-MRSA agent 24
Cat. No.:
HY-170847
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