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Cat. No.: HY-170847

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Anti-MRSA agent 24

Anti-MRSA agent 24 (compound 6K) is an antimicrobial agent that targets Staphylococcus aureus (MRSA), especially penicillin-resistant Staphylococcus aureus.

For research use only. We do not sell to patients.

CAS No.: 2379890-92-1
Formula: C₁₉H₁₃F₅N₂O₂
Molecular Weight:396.31

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Anti-MRSA agent 24 Chemical Structure

CAS No.: 2379890-92-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

Anti-MRSA agent 24 (compound 6K) is an antimicrobial agent that targets Staphylococcus aureus (MRSA), especially penicillin-resistant Staphylococcus aureus^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
CHO-K1	IC₅₀	6.9 μM Compound: 6u	Cytotoxicity against CHOK1 cells assessed as reduction in cell viability Cytotoxicity against CHOK1 cells assessed as reduction in cell viability	[PMID: 31624041]
HFL1	IC₅₀	15.6 μM Compound: 6u	Cytotoxicity against human HFL1 cells assessed as reduction in cell viability Cytotoxicity against human HFL1 cells assessed as reduction in cell viability	[PMID: 31624041]
L929	IC₅₀	15.8 μM Compound: 6u	Cytotoxicity against mouse L929 cells assessed as reduction in cell viability Cytotoxicity against mouse L929 cells assessed as reduction in cell viability	[PMID: 31624041]
NIH3T3	IC₅₀	65.6 μM Compound: 6u	Cytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability Cytotoxicity against mouse NIH/3T3 cells assessed as reduction in cell viability	[PMID: 31624041]
Vero	CC₅₀	>25 μM Compound: 6u	Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability	[PMID: 31624041]
Vero	IC₅₀	0.086 μM Compound: 6u	Antiviral activity against MERS-CoV KOR/KNIH/002_05_2015 infected in African green monkey Vero cells expressing viral spike protein by immunofluorescence assay Antiviral activity against MERS-CoV KOR/KNIH/002_05_2015 infected in African green monkey Vero cells expressing viral spike protein by immunofluorescence assay	[PMID: 31624041]

Chemical Information

CAS No. 2379890-92-1
Molecular Weight 396.31
Formula C₁₉H₁₃F₅N₂O₂
SMILES

FC1=CC(F)=C(NC(NC2=CC=C(F)C(F)=C2F)=C(C(C(C)C)=O)C3=O)C3=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lee J Y, et al. Discovery of 3-acyl-2-anilino-1, 4-dihydroquinolin-4-one derivatives as potential inhibitors of methicillin-resistant Staphylococcus aureus[J]. Bioorganic & Medicinal Chemistry Letters, 2025, 118: 130084.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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