Antibacterial agent 105

Cat. No.: HY-146098: Data Sheet Handling Instructions
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Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones show antibacterial activity against M. tuberculosis with antibacterial activity (MIC₉₀=2.64 μM). Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC₉₀s of 11.18, 11.18, 0.70, 1.40, 44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum, BCG, E. aerogenes and S. aureus, respectively.

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Antibacterial agent 105 화학구조

CAS No. : 2364493-24-1

사이즈		재고
MOQ		Minimum order quantity
50 mg		견적 받기
100 mg		견적 받기
250 mg		견적 받기
Other size		견적 받기

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Biological Activity
순도&문서
References
고객리뷰

제품 설명	Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones show antibacterial activity against M. tuberculosis with antibacterial activity (MIC₉₀=2.64 μM). Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC₉₀s of 11.18, 11.18, 0.70, 1.40, 44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum, BCG, E. aerogenes and S. aureus, respectively^[1].
In Vitro	Antibacterial agent 105 (compound 17) has inhibitory effect on the growth of M. tuberculosis replicating in vitro cultured macrophages^[1]. Antibacterial agent 105 (compound 17) (24 hours) has no toxicity on Vero cells line and human macrophages^[1]. Antibacterial agent 105 (compound 17) has antibacterial activities against FQ resistant bacteria and XDR-TB^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Antibacterial agent 105 Related Antibodies
분자량	299.24
화학식	C₁₄H₉N₃O₅
CAS No.	2364493-24-1
SMILES	O=C(C1=CN(C)C2=C(C1=O)C=C([N+]([O-])=O)C3=CC=CN=C32)O
선적	Room temperature in continental US; may vary elsewhere.
보관	Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서	Data Sheet (273 KB) Handling Instructions (2659 KB)
References	[1]. Songuigama Coulibaly, et al. Phenanthrolinic analogs of quinolones show antibacterial activity against M. tuberculosis. Eur J Med Chem. 2020 Dec 1;207:112821. [Content Brief]