AGTPBP1 Antibody (YA8265)(PBS only)

Cat. No.: HY-P88581A: Data Sheet User Guide for Antibodies
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Technical Support

AGTPBP1 Antibody (YA8265) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to AGTPBP1.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명
References

제품 설명

AGTPBP1 Antibody (YA8265) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to AGTPBP1.

Host

Mouse

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9UPW5

Immunogen

Human recombinant protein fragment corresponding to amino acids 368-753 of human AGTPBP1 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
FC FC: Flow Cytometry	1:100

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Metallocarboxypeptidase that mediates protein deglutamylation of tubulin and non-tubulin target proteins (PubMed:22170066, PubMed:24022482, PubMed:30420557). Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of alpha- and beta-tubulin (PubMed:22170066, PubMed:24022482, PubMed:30420557). Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate (PubMed:24022482). Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of alpha-tubulin as well as non-tubulin proteins such as MYLK (PubMed:22170066). Involved in KLF4 deglutamylation which promotes KLF4 proteasome-mediated degradation, thereby negatively regulating cell pluripotency maintenance and embryogenesis (PubMed:29593216)

Subcellular Localization：Cytoplasm,Cytoplasm, cytosol,Nucleus,Mitochondrion

Isoforms & Post-Translational Modification：Q9UPW5 has three isomers: Q9UPW5-1: 138448 Da (predicted); Q9UPW5-2: 133864 Da (predicted); Q9UPW5-3: 138647 Da (predicted).

Subunit：Interacts with MYLK

Synonyms

CCP1; NNA1

각종 서류

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/u2os-cell.html [Content Brief]