Anterior Gradient 2 Antibody (YA1779)(PBS only)

Cat. No.: HY-P82034A: Data Sheet User Guide for Antibodies
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Anterior Gradient 2 Antibody (YA1779) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Anterior Gradient 2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Anterior Gradient 2 Antibody (YA1779) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Anterior Gradient 2.

Host

Rabbit

Molecular Weight

Predicted band size: 20 kDa;

Observed band size: 20 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Rat

SwissProt ID

O95994

Gene ID

10551 [NCBI]

Immunogen

A synthetic peptide of human Anterior Gradient 2

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
IHC-F IHC-F: Immunohistochemistry-Frozen	1:50-1:100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200
IP IP: Immunoprecipitation	1:20

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Promotes cell adhesion (PubMed:23274113)

Subcellular Localization：Secreted; Endoplasmic reticulum

Expression：
Tissue_specificity:It is highly expressed in the trachea, lungs, stomach, colon, prostate, and small intestine. It is lowly expressed in the pituitary gland, salivary glands, mammary glands, bladder, appendix, ovary, fetal lungs, uterus, pancreas, kidneys, fetal kidneys, testes, placenta, thyroid gland, and estrogen receptor (ER) positive breast cancer cell lines.

Subunit：Monomer and homodimer (PubMed:23274113). Interacts with LYPD3 and DAG1 (alphaDAG1) (PubMed:12592373). Interacts with MUC2; disulfide-linked (PubMed:19359471, PubMed:34237462)

Research Field

Cancer

Synonyms

Anterior gradient protein 2 homolog; AG-2; hAG-2; HPC8; Secreted cement gland protein XAG-2 homolog; AGR2; AG2; GOB4; XAG2

Documentation

User Guide for Antibodies (1077 KB)