Aspartate Aminotransferase Antibody (YA2175)(PBS only)

Cat. No.: HY-P82430A: Data Sheet User Guide for Antibodies
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Aspartate Aminotransferase Antibody (YA2175) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Aspartate Aminotransferase.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

Aspartate Aminotransferase Antibody (YA2175) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Aspartate Aminotransferase.

Host

Rabbit

분자량

Predicted band size: 46 kDa;

Observed band size: 46 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P17174

Gene ID

2805 [NCBI]

Immunogen

A synthetic peptide of human Aspartate Aminotransferase aa197-210.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
IHC-F IHC-F: Immunohistochemistry-Frozen	1:50-1:100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Biosynthesis of L-glutamate from L-aspartate or L-cysteine (PubMed:21900944). Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain. In addition, catalyzes (2S)-2-aminobutanoate, a by-product in the cysteine biosynthesis pathway (PubMed:27827456)

Subcellular Localization：Cytoplasm

Isoforms & Post-Translational Modification：P17174 has 2 isomers: P17174-1: 46248 Da (predicted); P17174-2: 44147 Da (predicted).

Subunit：Homodimer

Research Field

Signal Transduction

Synonyms

Aspartate aminotransferase; cytoplasmic; Glutamate oxaloacetate transaminase 1; Transaminase A

각종 서류

User Guide for Antibodies (1077 KB)