ATRIP Antibody (YA2965)
(Synonyms: AGS1; ATIP; Atrip)
Based on 1 Customer Validation
ATRIP Antibody (YA2965) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATRIP.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-1:2000 | 1:50-1:200 |
Product Details
ATRIP Antibody (YA2965) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATRIP.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 86 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 86 kDa
Entrez Gene: 84126 Human ; 235610 Mouse ; 301014 Rat
SwissProt: Q8WXE1 Human ; Q8BMG1 Mouse ;
OMIM: 606605 Human
A synthesized peptide derived from human ATRIP aa202-250.
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
ATRIP is required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein
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Subcellular Localization
Nucleus
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Expression
Tissue_specificity:Ubiquitous -
Isoforms & Post-Translational Modification
Q8WXE1 has 4 isomers: Q8WXE1-1: 85838 Da (predicted); Q8WXE1-2: 83003 Da (predicted); Q8WXE1-3: 76336 Da (predicted); Q8WXE1-5: 72362 Da (predicted).
Phosphorylated by ATR -
Subunit
Interacts with ATR (By similarity). Heterodimer with ATR. The heterodimer binds the RPA complex and is then recruited to single-stranded DNA. Interacts with CEP164 (via N-terminus). Interacts with CINP
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SwissProt ID
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Synonyms
AGS1; ATIP; Atrip
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Research Field
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Documentation
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