C16orf72 Antibody (YA8498)

Cat. No.: HY-P88814: Fiche technique User Guide for Antibodies
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C16orf72 Antibody (YA8498) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to C16orf72.

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Size		Stock
50 μL		Obtenir un devis
100 μL		Obtenir un devis

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Description

Description

C16orf72 Antibody (YA8498) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to C16orf72.

Host

Mouse

Clonality

Monoclonal

Masse moléculaire

Predicted band size: 30.7 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q14CZ0

Immunogen

Full length human recombinant protein of human C16orf72 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:2000-3000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Pureté	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Livraison

Shipping with blue ice.

Background

Function：Acts as a central player within a network of stress response pathways promoting cellular adaptability. The E3 ligase HUWE1 assists HAPSTR1 in controlling stress signaling and in turn, HUWE1 feeds back to promote the degradation of HAPSTR1. HAPSTR1 represents a central coordination mechanism for stress response programs (PubMed:35776542). Functions as a negative regulator of TP53/P53 in the cellular response to telomere erosion and probably also DNA damage (PubMed:33660365). May attenuate p53/TP53 activation through the E3 ubiquitin ligase HUWE1 (PubMed:33660365)

Subcellular Localization：Nucleus,Cytoplasm

Expression：Induction: Induced by specific types of stressors like DNA damage, cellular starvation and proteotoxicity

Isoforms & Post-Translational Modification：Q14CZ0 has two isomers: Q14CZ0-1: 30926 Da (predicted); Q14CZ0-2: 22651 Da (predicted).
Ubiquitinated by HUWE1

Subunit：Homooligomer (PubMed:35776542)

Synonyms

PRO0149

Documentation

User Guide for Antibodies (1077 KB)