CD109 Antibody (YA4344)
(Synonyms: p180; r150; CPAMD7)CD109 Antibody (YA4344) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD109.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ICC/IF, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:20-1:100 | 1:200-1:400 | 1:10000 |
Product Details
CD109 Antibody (YA4344) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD109.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 180 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 161.7 kDa
Purified recombinant fragment of human CD109 (AA: extra 1274-1421) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD109 modulates negatively TGFB1 signaling in keratinocytes
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Subcellular Localization
Cell membrane; Lipid-anchor, GPI-anchor
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Expression
Tissue_specificity:Widely expressed with high level in uterus, aorta, heart, lung, trachea, placenta and in fetal heart, kidney, liver, spleen and lung. Expressed by CD34 (+) acute myeloid leukemia cell lines, T-cell lines, activated T-lymphoblasts, endothelial cells and activated platelets. Isoform 4 is expressed in placenta. Isoform 1 is expressed in keratinocytes and placenta -
Isoforms & Post-Translational Modification
Q6YHK3 has 4 isomers: Q6YHK3-1: 161689 Da (predicted); Q6YHK3-2: 152663 Da (predicted); Q6YHK3-3: 74411 Da (predicted); Q6YHK3-4: 159696 Da (predicted).
N-glycosylated;2 forms of 150 (p150) and 120 kDa (p120) exist due to proteolytic degradation from a 180 kDa form -
Subunit
Heterodimer; disulfide-linked. Interacts with TGFB1 and TGFBR1. Forms a heteromeric complex with TGFBR1, TGFBR2 and TGFBR3 in a ligand-independent manner
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SwissProt ID
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Synonyms
p180; r150; CPAMD7
Documentation
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