CD40 Antibody (YA5524)
(Synonyms: CD40; TNFRSF5; Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40; CD antigen CD40)CD40 Antibody (YA5524) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD40.
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Host:
Mouse
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Isotype:
IgG
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Application:
FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in Phosphate-buffered solution
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:5000-100000 | 1-2μg/Test |
Product Details
CD40 Antibody (YA5524) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD40.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 30 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Purified recombinant human CD40.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in Phosphate-buffered solution
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD40, also known as Bp50 and TNFRSF5, is a type I transmembrane protein which belongs to the TNF receptor (TNFR) superfamily. It is expressed on APC such as dendritic cells (DC), B cells, and monocytes as well as many non-immune cells and a wide range of
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Subcellular Localization
Cell membrane; Single-pass type I membrane protein; Secreted
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Expression
Tissue_specificity:B-cell and primary cancer -
Isoforms & Post-Translational Modification
P25942 has 2 isomers: P25942-1: 30619 Da (predicted); P25942-2: 22259 Da (predicted).
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Subunit
Monomer and homodimer. The variant form found in the bladder carcinoma cell line Hu549 does not form homodimers. Interacts with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6. Interacts with TRAF6 and MAP3K8; the interaction is required for ERK activation
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SwissProt ID
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Synonyms
CD40; TNFRSF5; Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40; CD antigen CD40
Documentation
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