CD57 Antibody (YA4546)(PBS only)

製品番号: HY-P84849A: データシート User Guide for Antibodies
FAQs
Technical Support

CD57 Antibody (YA4546) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD57.

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容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

CD57 Antibody (YA4546) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD57.

Host

Mouse

分子量

Predicted band size: 38 kDa;

Observed band size: 45/70 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q9P2W7

Gene ID

27087 [NCBI]

Immunogen

Purified recombinant fragment of human B3GAT1 (AA: 193-334) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

純度	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group

Subcellular Localization：Golgi apparatus membrane; Single-pass type II membrane protein; Secreted; Golgi apparatus membrane; Single-pass type II membrane protein; Endoplasmic reticulum membrane; Secreted

Expression：
Tissue_specificity:Primarily expressed in the brain

Isoforms & Post-Translational Modification：Q9P2W7 has 2 isomers: Q9P2W7-1: 38256 Da (predicted); Q9P2W7-2: 39738 Da (predicted).
The soluble form derives from the membrane form by proteolytic processing

Subunit：Homodimer. Interacts with SAR1A

Synonyms

NK1; CD57; HNK1; LEU7; NK-1; GLCATP; GLCUATP

ドキュメンテーション

User Guide for Antibodies (1077 KB)

CD57 Antibody (YA4546)(PBS only) 関連分類

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CD57 Antibody (YA4546)(PBS only)

Product Detail

Background

説明

CD57 Antibody (YA4546)(PBS only) 関連分類

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