CD63 Antibody (YA530)

Cat. No.: HY-P80604: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

CD63 Antibody (YA530) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD63.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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CD63 Antibody (YA530) Featured Recommendations:

3 Publications Citing Use of MCE CD63 Antibody (YA530)

: CD63 Antibody (YA530) purchased from MCE. Usage Cited in: J Transl Med. 2025 Jan 31;23(1):142. [Abstract]; Western blot analysis detecting the expression of exosome marker proteins CD63 and TSG101.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Verification Image
Background
Documentation

Description

CD63 Antibody (YA530) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD63.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 26 kDa;

Observed band size: 40-70 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Mouse

SwissProt ID

P41731

Gene ID

967 [NCBI]

Immunogen

Synthetic peptide corresponding to Mouse CD63.The exact sequence is proprietary to MCE.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100

Sensitivity	Endogenous	Purity	affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

1.Supplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA. Preservative: 0.01% Sodium azide
2.Supplied in PBS(pH 7.4), 150mM NaCl, 50% Glycerol, 0.02% Sodium azide and 0.05% BSA.
Please refer to the lot-specific COA for specific buffer information.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Verification Image

Western blot analysis of extracts from RAW264.7(lane 2(20μg) and RAW264.7(lane 3(40μg) using CD63 Antibody (HY-P80604) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

Background

Function：Functions as a cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli

Subcellular Localization：Cell membrane; Multi-pass membrane protein; Lysosome membrane; Multi-pass membrane protein; Late endosome membrane; Multi-pass membrane protein; Endosome, multivesicular body; Melanosome; Secreted, extracellular exosome; Cell surface

Expression：
Tissue_specificity:Ubiquitous. Strongly expressed in kidney. Detected in spleen, bone marrow, peripheral blood mononuclear cells and macrophages

Subunit：Interacts with TIMP1 and ITGB1 and recruits TIMP1 to ITGB1. Interacts with CD9. Identified in a complex with CD9 and ITGB3. Interacts with PMEL.

RRID

AB_3102625

Database

Entrez Gene: 967 Human ; 12512 Mouse ;

SwissProt: P08962 Human ; P41731 Mouse ;

OMIM: 155740 Human

Research Field

Cardiovascular

Synonyms

CD63 antigen; CD63

Documentation

Select Batch:

Data Sheet (232 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

CD63 Antibody (YA530) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CD63 Antibody (YA530)

CD63 Antibody (YA530) Featured Recommendations:

3 Publications Citing Use of MCE CD63 Antibody (YA530)

Product Detail

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Background

Documentation

CD63 Antibody (YA530) Related Classifications

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