CD70 Antibody (YA4697)
(Synonyms: CD70; CD27L; CD27LG; TNFSF7; CD70 antigen; CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD antigen CD70; CD70 nanobody; )CD70 Antibody (YA4697) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD70.
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Host:
Mouse
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Application:
ELISA, FC
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Reactivity :
Human
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Formulation:
Supplied in Phosphate-buffered solution.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:5000-100000 | 1-2μg/Test |
Product Details
CD70 Antibody (YA4697) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD70.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
Purified recombinant Human CD70
affinity purified.
Non-conjugated
Unmodified
Product Properties
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Appearance
Liquid
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Formulation
Supplied in Phosphate-buffered solution.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD70 is expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells. The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells[1][2][3].
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Subcellular Localization
Cell membrane; Single-pass type II membrane protein
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Isoforms & Post-Translational Modification
P32970 has 2 isomers: P32970-1: 21118 Da (predicted); P32970-2: 23438 Da (predicted).
N-glycosylated -
Subunit
Homotrimer
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SwissProt ID
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Synonyms
CD70; CD27L; CD27LG; TNFSF7; CD70 antigen; CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD antigen CD70; CD70 nanobody;
Documentation
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