CDC7 Antibody (YA7721)
CDC7 Antibody (YA7721) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC7.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:50-100 |
Product Details
CDC7 Antibody (YA7721) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC7.
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Host Rabbit
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Clonality Recombinant
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 70 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 64 kDa
A synthesized peptide derived from human CDC7
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CDC7 is a Kinase involved in initiation of DNA replication. Phosphorylates critical substrates that regulate the G1/S phase transition and initiation of DNA replication, such as MCM proteins and CLASPIN
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
O00311 has one isomer, O00311-1: 63888 Da (predicted).
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Subunit
Forms a complex with either DBF4/DBF4A or DBF4B, leading to the activation of the kinase activity (PubMed:10373557, PubMed:12065429, PubMed:15668232, PubMed:17062569)
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SwissProt ID
Documentation