Copy Link Print Information

CGRP Antibody (YA6505)

(Synonyms: Calcitonin/calcitonin related polypeptide alpha antibody; Alpha type CGRP antibody; Beta type CGRP antibody; CALC1 antibody; CALC2 antibody; CALCA antibody; CALCB antibody; Calcitonin 1 antibody; Calcitonin 2 antibody; Calcitonin gene related peptide I antibody; Calcitonin/calcitonin related polypeptide alpha antibody; Alpha type CGRP antibody; Beta type CGRP antibody; CALC1 antibody; CALC2 antibody; CALCA antibody; CALCB antibody; Calcitonin 1 antibody; Calcitonin 2 antibody; Calcitonin gene related peptide I antibody; Calcitonin gene related peptide II antibody; Calcitonin related polypeptide alpha antibody; Calcitonin related polypeptide beta antibody; CGRP antibody; CGRP I antibody; CGRP II antibody; CGRP1 antibody; CGRP2 antibody; CT antibody; Katacalcin antibody; KC antibody; )
Customer Review

Based on 1 Customer Validation

CGRP Antibody (YA6505) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CGRP.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, ICC/IF, IHC-P, FC, IHC-F

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Conjugation:
    Non-conjugated
  • Experimental Validation Results for CGRP Antibody (YA6505)
  • Experimental Validation Results for CGRP Antibody (YA6505)
  • CGRP Antibody (YA6505) Product Image
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Service
Data Download
Related Products:
Top Publications Citing

Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
FC Info
FC: Flow Cytometry
IHC-F Info
IHC-F: Immunohistochemistry-Frozen
Dilution Ratio 1:2000 1:100 1:200-1:1000 1:10000 1:500

Product Details

Description

CGRP Antibody (YA6505) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CGRP.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 10 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 14 kDa
Species Reactivity Database
Immunogen

Recombinant protein within rat CGRP aa 1-128.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

RRID

AB_3719216

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Verification Images

  • Experimental Validation Results for CGRP Antibody (YA6505)
    Immunohistochemical analysis of paraffin-embedded rat colon tissue using CGRP Antibody. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked in QuickBlock for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody at 1/100 dilution in 4℃ overnight. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
  • Experimental Validation Results for CGRP Antibody (YA6505)
    Immunohistochemical analysis of paraffin-embedded rat colon tissue using CGRP Antibody. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked in QuickBlock for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody at 1/100 dilution in 4℃ overnight. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

Background

  • Function

    CGRP is a CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex. Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. CGRP1 can also bind and activate CALCR-RAMP1 (AMYR1) receptor complex[1][2][3][4][5].

  • Subcellular Localization

    Secreted

  • Expression


    Tissue_Specificity: Expressed in spinal cord

  • Isoforms & Post-Translational Modification

    P06881 has three isomers: P06881-1: 13899 Da (predicted); P01258-1: 15467 Da (predicted); P01258-2: 15535 Da (predicted).

  • SwissProt ID

    P01256

  • Gene ID
    796 [NCBI]
  • Synonyms

    Calcitonin/calcitonin related polypeptide alpha antibody; Alpha type CGRP antibody; Beta type CGRP antibody; CALC1 antibody; CALC2 antibody; CALCA antibody; CALCB antibody; Calcitonin 1 antibody; Calcitonin 2 antibody; Calcitonin gene related peptide I antibody; Calcitonin/calcitonin related polypeptide alpha antibody; Alpha type CGRP antibody; Beta type CGRP antibody; CALC1 antibody; CALC2 antibody; CALCA antibody; CALCB antibody; Calcitonin 1 antibody; Calcitonin 2 antibody; Calcitonin gene related peptide I antibody; Calcitonin gene related peptide II antibody; Calcitonin related polypeptide alpha antibody; Calcitonin related polypeptide beta antibody; CGRP antibody; CGRP I antibody; CGRP II antibody; CGRP1 antibody; CGRP2 antibody; CT antibody; Katacalcin antibody; KC antibody;

CGRP Antibody (YA6505) Related Classifications

MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00

Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • 1/16

    MedchemExpress Validation
     Immunohistochemical analysis of paraffin-embedded rat colon tissue using CGRP Antibody. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked in QuickBlock for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody at 1/100 dilution in 4℃ overnight. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

  • 1/16

    MedchemExpress Validation
     Immunohistochemical analysis of paraffin-embedded rat colon tissue using CGRP Antibody. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked in QuickBlock for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody at 1/100 dilution in 4℃ overnight. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

  • CGRP Antibody (YA6505) Product Image
    1/16
  • Experimental Validation Results for CGRP Antibody (YA6505)
  • Experimental Validation Results for CGRP Antibody (YA6505)
  • CGRP Antibody (YA6505) Product Image
  • Experimental Validation Results for CGRP Antibody (YA6505)
    1/1
    MedchemExpress Validation
     Immunohistochemical analysis of paraffin-embedded rat colon tissue using CGRP Antibody. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked in QuickBlock for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody at 1/100 dilution in 4℃ overnight. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
  • Experimental Validation Results for CGRP Antibody (YA6505)
    1/1
    MedchemExpress Validation
     Immunohistochemical analysis of paraffin-embedded rat colon tissue using CGRP Antibody. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked in QuickBlock for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody at 1/100 dilution in 4℃ overnight. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
  • Experimental Validation Results for CGRP Antibody (YA6505)
  • Experimental Validation Results for CGRP Antibody (YA6505)
  • CGRP Antibody (YA6505) Product Image
    MedchemExpress Validation

    Immunohistochemical analysis of paraffin-embedded rat colon tissue using CGRP Antibody. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked in QuickBlock for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody at 1/100 dilution in 4℃ overnight. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

  • CGRP Antibody (YA6505) Product Image
    MedchemExpress Validation

    Immunohistochemical analysis of paraffin-embedded rat colon tissue using CGRP Antibody. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 8 minutes. The tissues were blocked in QuickBlock for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody at 1/100 dilution in 4℃ overnight. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

  • CGRP Antibody (YA6505) Product Image IHC-P
  • CGRP Antibody (YA6505) Product Image IHC-P