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CRYZL1 Antibody (YA8477)(PBS only)

(Synonyms: 4P11; QOH-1)

CRYZL1 Antibody (YA8477) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CRYZL1.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2b

  • Application:

    WB, IHC-P, ICC/IF, FC

  • Reactivity :

    Human, Monkey, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • CRYZL1 Antibody (YA8477)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:500-2000 1:150-500 1:100-250 1:100

Product Details

Description

CRYZL1 Antibody (YA8477) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CRYZL1.

  • Host Mouse
  • Species Reactivity
    Human, Monkey, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 38.5 kDa
Immunogen

Full length human recombinant protein of human CRYZL1 produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG2b

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    CRYZL1 component of the FERRY complex (Five-subunit Endosomal Rab5 and RNA/ribosome intermediary). The FERRY complex directly interacts with mRNAs and RAB5A, and functions as a RAB5A effector involved in the localization and the distribution of specific mRNAs most likely by mediating their endosomal transport. The complex recruits mRNAs and ribosomes to early endosomes through direct mRNA-interaction[1][2].

  • Subcellular Localization

    Early endosome

  • Expression


    Tissue_Specificity: Ubiquitous

  • Isoforms & Post-Translational Modification

    O95825 has two isomers: O95825-1: 38697 Da (predicted); O95825-2: 21928 Da (predicted).

  • Subunit

    Homodimer (PubMed:37267906)

  • SwissProt ID

    O95825

  • Synonyms

    4P11; QOH-1

CRYZL1 Antibody (YA8477)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • CRYZL1 Antibody (YA8477)(PBS only) Product Image
    1/16
  • CRYZL1 Antibody (YA8477)(PBS only) Product Image