Cytokeratin 14 Antibody (YA5937)
Cytokeratin 14 Antibody (YA5937) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytokeratin 14.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF, IP, ELISA
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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IP
IP: Immunoprecipitation
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|---|---|---|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:2000-1:10000 | 1:200-1:1000 | 1:5000-1:20000 | 1:50-1:200 |
Product Details
Cytokeratin 14 Antibody (YA5937) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytokeratin 14.
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Host Rabbit
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 52 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 52 kDa
Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Cytokeratin 14 is a The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro
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Subcellular Localization
Cytoplasm; Nucleus
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Expression
Tissue_specificity:Expressed in the corneal epithelium (protein level) (PubMed:26758872) . Detectable in the basal layer, with decreased expression in higher layers, particularly the spinous and granular layers, but not detected in the stratum corneum. Strongly expressed in the outer root sheath of hair follicles during the anagen phase, but not in the germinal stroma, inner root sheath, or hair itself (PubMed:9457912) . Found in keratinocytes surrounding the hair bulb during the telogen phase (PubMed:9457912) . -
Subunit
Forms a disulfide-linked heterodimer (via 2B domains) with KRT5 (via 2B domains) (PubMed:22705788, PubMed:24940650).
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SwissProt ID
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