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Cytokeratin 16 Antibody (YA5594)

(Synonyms: CK 16; CK-16; CK16; Cytokeratin 16; CytokeRatin-16; CytokeRatin16; FNEPPK; Focal non epidermolytic palmoplantar keRatoderma; K 16; K16; K1C16_HUMAN; K1CP; KeRatin 1 type I; KeRatin 16; KeRatin; KeRatin type I cytoskeletal 16; KeRatin-16; KeRatin16; KRT 16; Krt16; KRT16A; NEPPK; PC1; type I cytoskeletal 16)

Cytokeratin 16 Antibody (YA5594) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Cytokeratin 16.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2b

  • Application:

    IHC-P, WB, ICC/IF, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • Conjugation:
    Non-conjugated
  • Cytokeratin 16 Antibody (YA5594) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
WB Info
WB: Western Blot
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:200-1000 1:500-2000 1:100-500 1:1000-5000

Product Details

Description

Cytokeratin 16 Antibody (YA5594) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Cytokeratin 16.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 55 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 51 kDa
Immunogen

Synthesized peptide derived from human CK16 AA range: 400-473

Purification

Protein G

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG2b

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Cytokeratin 16 is an Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance

  • Expression


    Tissue_specificity:Expression (protein level) in corneal epithelial cells

  • Subunit

    Heterodimer of a type I and a type II keratin. KRT16 associates with KRT6 isomers (KRT6A or KRT6B) (By similarity). Interacts with TCHP (PubMed:15731013). Interacts with TRADD (By similarity)

  • SwissProt ID

    P08779

  • Gene ID
    3868 [NCBI]
  • Synonyms

    CK 16; CK-16; CK16; Cytokeratin 16; CytokeRatin-16; CytokeRatin16; FNEPPK; Focal non epidermolytic palmoplantar keRatoderma; K 16; K16; K1C16_HUMAN; K1CP; KeRatin 1 type I; KeRatin 16; KeRatin; KeRatin type I cytoskeletal 16; KeRatin-16; KeRatin16; KRT 16; Krt16; KRT16A; NEPPK; PC1; type I cytoskeletal 16

Cytokeratin 16 Antibody (YA5594) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • Cytokeratin 16 Antibody (YA5594) Product Image
    1/16
  • Cytokeratin 16 Antibody (YA5594) Product Image