Cytokeratin 6 Antibody (YA7303)
(Synonyms: K6A, KRT6D, KRT6A, Cytokeratin-6A, Cytokeratin-6D, Keratin-6A, Type-II keratin Kb6, CK-6A, CK-6D)Based on 1 Customer Validation
Cytokeratin 6 Antibody (YA7303) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytokeratin 6.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IHC-F, IF-Tissue, FC
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Reactivity :
Human
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Formulation:
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% glycerol.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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FC
FC: Flow Cytometry
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|---|---|---|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:100-500 | 1:100-500 | 1:100-500 | 1:50-100 |
Product Details
Cytokeratin 6 Antibody (YA7303) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytokeratin 6.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman Predicted Reactivity: HumanNote: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
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Observed Molecular WeightObserved band size: 56 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 60 kDa
A synthesized peptide derived from human Cytokeratin 6: 500-564.
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% glycerol.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Cytokeratin 6 is a P02538: Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair.
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Expression
Tissue_Specificity: Constitutively expressed in distinct types of epithelia such as those in oral mucosa, esophagus, papillae of tongue and hair follicle outer root sheath -
Isoforms & Post-Translational Modification
Cytokeratin 6: 564 amino acids, molecular weight 60,025 Da.
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Subunit
Heterodimer of a type I and a type II keratin. KRT6 isomers associate with KRT16 and/or KRT17
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SwissProt ID
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Synonyms
K6A, KRT6D, KRT6A, Cytokeratin-6A, Cytokeratin-6D, Keratin-6A, Type-II keratin Kb6, CK-6A, CK-6D
Documentation