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EDR1/PHC1 Antibody (YA7127)(PBS only)

(Synonyms: EDR1, PH1, PHC1, Polyhomeotic-like protein 1, hPH1, Early development regulatory protein 1)

EDR1/PHC1 Antibody (YA7127) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EDR1/PHC1.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • EDR1/PHC1 Antibody (YA7127)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:200-1:400 1:10000

Product Details

Description

EDR1/PHC1 Antibody (YA7127) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EDR1/PHC1.

  • Host Mouse
  • Species Reactivity
    Human
  • Calculated Molecular Weight Predicted band size: 105.5kDa;
Immunogen

Purified recombinant fragment of human PHC1 (AA: 758-1004) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    EDR1/PHC1 component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Required for proper control of cellular levels of GMNN expression

  • Subcellular Localization

    Nucleus

  • Isoforms & Post-Translational Modification

    P78364: 1004 amino acids, molecular weight 105534 Da.

  • Subunit

    Homodimer

  • SwissProt ID

    P78364

  • Synonyms

    EDR1, PH1, PHC1, Polyhomeotic-like protein 1, hPH1, Early development regulatory protein 1

EDR1/PHC1 Antibody (YA7127)(PBS only) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • EDR1/PHC1 Antibody (YA7127)(PBS only) Product Image