Fatty Acid Synthase Antibody (YA5189)

製品番号: HY-P85497: データシート User Guide for Antibodies
FAQs
Technical Support

Fatty Acid Synthase Antibody (YA5189) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Fatty Acid Synthase.

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容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

Fatty Acid Synthase Antibody (YA5189) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Fatty Acid Synthase.

Host

Mouse

Clonality

Monoclonal

分子量

Observed band size: 273 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat, Monkey, Bovine

SwissProt ID

P49327

Gene ID

2194 [NCBI]

Immunogen

Purified recombinant human Fatty Acid Synthase protein fragments expressed in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:400
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-200

純度	affinity chromatography.	Conjugation	Non-conjugated
Modification	Unmodified

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain; (Microbial infection) Fatty acid synthetase activity is required for SARS coronavirus-2/SARS-CoV-2 replication

Subcellular Localization：Cytoplasm; Melanosome

Expression：
Tissue_specificity:It is widely distributed. It is significantly expressed in the brain, lungs, liver, and breast.

Subunit：Homodimer which is arranged in a head to tail fashion (PubMed:17618296, PubMed:18022563, Ref.34). Interacts with CEACAM1; this interaction is insulin and phosphorylation-dependent; reduces fatty-acid synthase activity

Synonyms

[Acyl-carrier-protein] S acetyltransferase; [Acyl-carrier-protein] S malonyltransferase; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase; 3-oxoacyl-[acyl-carrier-protein] reductase; 3-oxoacyl-[acyl-carrier-protein] synthase; Enoyl-[acyl-carrier-protein]

ドキュメンテーション

User Guide for Antibodies (1077 KB)

Fatty Acid Synthase Antibody (YA5189) 関連分類

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Fatty Acid Synthase Antibody (YA5189)

Product Detail

Background

説明

Fatty Acid Synthase Antibody (YA5189) 関連分類

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