Gelsolin Antibody (YA1570)

Cat. No.: HY-P81825: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

Gelsolin Antibody (YA1570) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Gelsolin.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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Gelsolin Antibody (YA1570) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Gelsolin Antibody (YA1570) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Gelsolin.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 86 kDa;

Observed band size: 86 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse

SwissProt ID

P06396

Gene ID

2934 [NCBI]

Immunogen

A synthesized peptide derived from human Gelsolin aa450-485.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-1:200
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200
FC FC: Flow Cytometry	1:50-1:100

Sensitivity	Endogenous	Purity	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed (PubMed:19666512). Plays a role in ciliogenesis (PubMed:20393563)

Subcellular Localization：Cytoplasm, cytoskeleton; Secreted

Expression：
Tissue_specificity:Phagocytes, platelets, fibroblasts, non-muscle cells, smooth muscle cells, and skeletal muscle cells

Isoforms & Post-Translational Modification：P06396 has 4 isomers: P06396-1: 85698 Da (predicted); P06396-2: 80641 Da (predicted); P06396-3: 81941 Da (predicted); P06396-4: 81485 Da (predicted).
Phosphorylation on Tyr-86, Tyr-409, Tyr-465, Tyr-603 and Tyr-651 in vitro is induced in presence of phospholipids

Subunit：Binds to actin and to fibronectin. Identified in a complex composed of ACTA1, COBL, GSN and TMSB4X.

Database

Entrez Gene: 2934 Human ; 227753 Mouse ;

SwissProt: P06396 Human ; P13020 Mouse ;

OMIM: 105120 Human

Research Field

Signal Transduction

Synonyms

ADF; AGEL; Brevin; Gelsolin; Gsn

Documentation

Select Batch:

Data Sheet (234 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

Gelsolin Antibody (YA1570) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Gelsolin Antibody (YA1570)

Gelsolin Antibody (YA1570) Featured Recommendations:

Product Detail

Background

Documentation

Gelsolin Antibody (YA1570) Related Classifications

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